BS in Biochemistry & Biotechnology

Overview




Biochemistry is the study of the molecular reactions of life, whereas Biotechnology focuses on the application of this knowledge. Biochemistry has taken the forefront in defining broadly based opportunities in Biotechnology applications that indicate the path for biologically based future of the twenty-first century. The two disciplines go hand in hand and now-a-days there is little distinction between the two. The Bachelor of Science in Biochemistry and Biotechnology program at NSU is a merger of the above two disciplines, first of its kind in Bangladesh. The program integrates the molecular life sciences from the most basic biology-chemistry interface to advanced molecular biology, molecular genetics, bioinformatics and genetic engineering.

The program provides a 4-year academic program leading to the undergraduate BSc Honors degree in Biochemistry and Biotechnology. Majors have the opportunity through extensive coursework, laboratories, seminars and projects to develop the knowledge and skills necessary to enter the workforce or to go on with further graduate education leading to MSc or Ph.D degree in Biochemistry and Biotechnology or related subjects at home and abroad. Under the MOU signed between NSU and other national and international institutions, Department of Biochemistry & Microbiology will provide the students excellent laboratory and research facilities. Total credits for BS in Biochemistry & Biotechnology amounts to 133 credits.

Course Outline


Requirements for a FOUR YEAR Bachelor of Science degree in Biochemistry and Biotechnology:

Taught courses                       : 81 Credits*
Laboratory and seminar         : 25 Credits*
GED courses                           : 27 Credits

Total                                       : 133 Credits

*NB: Taught, laboratory and seminar courses are considered as core courses which are mandatory for Biochemistry and Biotechnology undergraduate program




1st Professional Year (33 or 36 credits):


 Courses

Titles

Semester

Credits

 BBT101

 Introductory Biochemistry

1

3

 BBT102

 Basic Microbiology

1

3

 ENG102*

 Introduction to Composition

1

3

 ENG103*

 Intermediate Composition

1 or 2

3

 BBT103

 Computer and Communications

2

3

 CHE101

 General Chemistry

2

3

 BBT116

 Math for Biologists

2

3

 SOC101

 Introduction to Sociology

2

3

 PSY101

 Introduction to Psychology

2

3

 BBT201

 Biophysical Chemistry

3

3

 BBT202

 Bioorganic Chemistry I

3

3

 BBT211

 Physics for Biologist

3

3

 BBT109

 Introductory organic chemistry and Microbiology lab

3

3

Total Credits

33 or 36


*NB: ENG102 and ENG103 are given to a student based on their performance in the English Section of the NSU admission test. The students who will be given ENG103 do not have to take ENG 102, whereas the student who is given ENG102 also needs to take ENG 103.

 

BBT101: Introduction to Biochemistry and Biotechnology (3 Credits)

This course introduces history, scope and future of Biochemistry and biotechnology. Students learn the basic logics of living organisms, the role of bio-molecules and their interrelationship. The course provides following introductory concepts: i) define and explain the basic concepts in biochemistry; ii) various biochemical pathways; iii) define the biological macromolecules and their subunits; iv) basic applied concepts in biochemistry to biotechnology; v) explain the underlying concepts in biotechnology; and vi) relate the biochemical properties and their principles as tools of biotechnology.

BBT102: Basic Microbiology (3 Credits)

Important historical developments which led to the formulation of the germ theory of disease and those discoveries that lead to the development of the science of biotechnology; historical background of the classification of microorganisms, and the techniques used to categorize them; differences between the old five-kingdom system and the modern three-domain system; structure and function of prokaryotic and eukaryotic cells; Bacterial growth curve- lag phase, exponential phase, stationary phase and death phase; archaeal diversity and life in extreme environment; survey of prokaryotic microorganisms with unusual characteristics; basic structure and characteristics of viruses, infection process with emphasis on animal viruses and bacteriophage; diversity and importance of eukaryotic microorganisms, namely protozoa, fungi and algae; nutritional requirement of microorgamisms and classification; cultivation of microorganisms in the laboratory.

 

BBT103: Computer and Communications  (3 Credits)

The students in Computer and Communications will be using personal computers in their everyday activities and projects. This subject will be covering four major areas: Windows; Microsoft Office applications, the Internet (Search engine and Introduction to Bioinformatics), and Draw/Paint. The students will acquire the basics of the Windows system so that they will be able to navigate with ease through the various applications they will be using throughout their graduation. Microsoft Office contains word processing, spreadsheet, and presentation applications—software that will be critical for degree and career success. All the computers in the class have Internet access. For many of their projects, the students will be working in collaborative groups. Students will be working side-by-side to complete exercises and produce final projects. This course has been provided to student as GED course.

 

CHE101: General Chemistry (3 Credits)

This course covers fundamental principles of chemistry. Topics include measurement, atomic and molecular structure, periodicity, chemical reactions, chemical bonding, stoichiometry, thermochemistry, Chemical Equilibrium and Kinetics, gas laws and solutions. This course is appropriate as a basic chemistry course or as a science elective for students who have science, engineering, or mathematics majors. Upon completion, students will be able to- Define chemistry as the study of matter, can apply the basic concepts in their future studies and apply safe laboratory skills to solve problems in a cooperative environment.

 

BBT116: Math for Biologists (3 Credits)

The major objective of the course is to provide a student majoring in the biological sciences a mastery of the basic concepts of mathematics of changing and explore some of its applications in related fields. The concepts of differentiation and integration of different functions including vectors and differential equations will be the major focus of this course. The emphasis will be given on analytical, numerical and graphical approach of these topics. This course has been provided to student as GED course.

 

BBT201: Biophysical Chemistry (3 Credits)

Thermodynamics - First law, Second law and Introduction, definitions, Thermodynamic terms and basic concepts; Thermochemistry, Exothermic and endothermic reactions, standard enthalpy of formation, thermochemical equations; The nature of chemical equilibrium, law of mass action, equilibrium constant,  relationship between ∆G and Keq, effect of temperature and pressure, Le Chatelier’s principle,, Chemical Kinetics and it Definition, reaction rate, rate laws, order reactions, molecularity of a reaction, pseudo first order reaction, half-life, Catalysis, Photochemistry and Spetrophotometry, Transmittance and absorbance, Beer-Lambert law, Properties of liquids, Acids and bases.

 

BBT202: Bio-organic Chemistry I (3 Credits)

This course is a comprehensive introduction in fundamental aspects of biological chemistry, for freshmen students. Knowledge of structure, functionality and reactivity of the organic molecules is vital for understanding the mechanism of numerous biological processes and biochemical reactions. This course provides a foundation of organic chemistry, i.e. the understanding of structure, properties, interactions, transformations and nomenclature of organic compounds. The Students attending the course will be able to recognize the major functional groups, write systematic names, draw accurate structures, correlate molecular structure with physical and chemical properties, categorize reactions by type, write or recognize essential reaction mechanisms, and recognize the structures and functions of the main classes of biomolecules.

 

BBT211: Physics for Biologist  (3 Credits) 

This course has been design especially for biological student in order to understand the concepts and principles of physics. In this course, we will discuss conceptual and quantitative problems and questions. A comprehensive coverage of subject matter in physics is presented, including mechanics, properties of matter, wave motions, electricity, magnetism, optics and atomic and nuclear physics. The major objective of the course is to provide a student majoring in the biological sciences a mastery of the basic concepts of physics and explore some of its applications in related fields.

 

BBT109: Introductory organic chemistry and Microbiology Lab  (3 Credits)

The basic idea of a biochemistry and microbiology laboratory will be provided in this course. The students will get practical experiences on the detection of an unknown organic compound based on their physical and chemical properties. Emphasis will be given on the nature of different biochemical solution and how to prepare them accurately. Moreover students will also get basic idea how to detect specific organic compound present in biological sample. In the microbiology section the basic laboratory skill will be discussed and student will learn the basic techniques to detect and isolate microorganisms from food and water samples.

2nd Professional Year (32 credits):

Courses

Titles

Semester

Credits

 BBT204

 Molecular Biology I

4

3

 BBT205

 Metabolism I

4

3

 BBT208

 Introduction to Nutrition

4

3

 BBT210

 Seminar I

4

2

 BBT206

 Proteins and Enzymes

5

3

 BBT209

 Biochemistry and Nutrition Lab

5

3

 BBT 301

 Bioorganic Chemistry II

5

3

 BBT207

 Human Physiology

6

3

 BBT303

 Basic Immunology

6

3

 ENG105

 Advanced Composition

6

3

 MIC307

 Microbial Genetics

6

3

Total Credits

32

 

BBT204: Molecular Biology I (3 Credits)

Important historical developments in genetics, particularly the contributions of Mendel, and Watson & Crick; and important research advances; Analysis of genetic problems using Punnett squares to illustrate Mendelian principles; Chromosome basis of inheritance, sex determination and sex linkage; types of chromosomal aberrations and their consequences; molecular genetics, gene function, the structure of genetic material; the organization of DNA in chromosomes; structure and replication of DNA, concepts of protein synthesis, gene expression, mutations, and genetic engineering;   transcription and the structural and functional features of the transcripts; genetic code and the translation of the genetic message.

 

BBT205: Metabolism I (3 Credits)                                                                                   

Bioenergetics and thermodynamics; The glycolytic pathway, two phases of glycolysis, Secondary pathways of glucose oxidation; The citric acid cycle: Steps and reactions involved, Metabolic fates of Amino groups, enzymatic degradation of the dietary proteins to amino acids, oxidative phosphorylation and photophosphorylation, The chemiosmotic model; regulation of oxidative phosphorylation by cellular energy needs, Gluconeogenesis and Reciprocal regulation of gluconeogenesis and glycolysis, Nitrogen metabolism, Integration and hormonal regulation of mammalian metabolism.

BBT208: Introduction to Nutrition (3 Credits) 

This course is intended for 2nd Year under-graduate students going to complete organic chemistry, biochemistry, molecular biology and physiology. Course will provide an integrated overview of the physiological requirements and functions of macro- and micro-nutrients that are determinants of health and diseases in human populations. The course provides an overview of the major macro- and micro-nutrients relevant to human health. Discuss the scientific rationale for defining nutritional requirements in healthy individuals and populations, with reference to specific conditions such as pregnancy, lactation, and older age. The topics will also cover current evidence for the role of key nutrients in the prevention of chronic diseases. Discuss major nutrition-related diseases in a global context.

 

BBT210: Seminar I (2 Credits)

The objective of this course is to give students the confidence to make oral presentations before small and large audiences and to train students in basic skills in preparing and delivering audio visual presentations, including audience interaction and effective use of visual aids. Students will prepare and present on various topics throughout the semester, which will be evaluated by the faculty. They will also be expected to answer questions and tackle problems during the presentation.

 

BBT206: Proteins and Enzymes (3 Credits)

The objective of this course is to provide understanding on protein structure, properties and their most important functions. Key concepts related to this course are studying properties of amino acids and peptides, reaction and analysis of amino acids, different structural level of organization of proteins with specific examples, how protein interact with other molecules related to their function and different analytical techniques use in protein chemistry. Studying enzymes and its classification, enzyme kinetics, enzymes mechanism of action, enzyme inhibition, regulation, and reaction mechanism of some enzymes and clinical, diagnostic and industrial application of enzymes are also key notions relation to this course. This course will be useful for future studies in biochemistry, microbiology, molecular and cellular biology, biotechnology, pharmaceutical and medically related fields.

 

BBT209: Biochemistry and Nutrition Lab (3 Credits) 

This laboratory course deals with two broad biological fields: biochemistry and nutrition. Main objective of the biochemistry part is to bring experience in solving practical problems in biochemistry laboratory, to acquire applicable skills and to teach students to derive conclusions from experiments. Biochemistry part also demonstrates methods of clinical biochemistry and their significance for diagnosis of diseases. The nutrition part is targeted at manufacturers, food technologists and quality control managers in the food industry and provides “hands-on” practical training to such personnel in analyzing accurate nutritional value in food samples using international standard methods. At the end of the course, participants should be able to use the various methods presented in the analysis of the nutritional content in their food products for quality control purpose.

 

BBT301: Bio-organic Chemistry II (3 Credits) 

The course starts with a review of organic functional groups structure & functions and stereochemistry. Later, the discussion will continue with the structures of small bio-molecules, e.g. carbohydrates, amino acids, nucleotides, and lipids. Next, the formation of large bio-molecules from these building blocks is described in terms of the RNA world hypothesis.  The chemistry behind both the formation and degradation of these compounds both in vitro and in vivo in the modern world will be covered through study of the properties of acetals, phosphate esters and amides with emphasis on learning about complex biological systems from simpler chemical ones. This course will help the students to understand complex biological interactions in terms of basic organic chemistry.

 

BBT207: Human Physiology (3 Credits) 

Physiology is the study of how living organism functions. The main theme of human physiology is the molecular and cellular interaction to maintain the constant internal environment, i.e. homeostasis. This course commences with the principles of physiology, which is followed by an elaborate discussion of molecular-cellular physiology with a specific focus on neural and endocrine control and integration of homeostasis. Individual organ systems, including musculoskeletal, circulatory, respiratory, digestive, urinary, and reproductive systems also given emphasis for a complete understanding that how human body functions.

 

BBT303: Basic Immunology (3 Credits)

The purpose of this course is to provide a basic knowledge of immunology. This course will provide in-depth understanding the cells, molecules and organs of the immune system and how they work   together to protect us from pathogen. The principal focus of the course will be on studying structural features of the components of the immune system and their functions, innate and adaptive branches of both humoral and cellular responses of the immune system. The course will also assign emphasis on learning the major mechanisms by which immune cells protect us from different types of pathogens or from cancer cells, how immune cells detect the presence of pathogens and cancer cells, processes that lead to the elimination of pathogens. Studying the structure and function of key immune recognition molecules including antigens, antibodies, antigen receptors, MHC proteins, cytokines are covered. The course will introduce some immunological assays to detect antigen-antibody interactions.

 

MIC307: Microbial Genetics (3 Credits)

Microbial Genetics and Genetic Materials; Bacterial transformation: Mechanisms, transformation analysis, Mapping by transformation, Bacterial conjugation: Lederberg and Tatum’s Experimental Design, Mapping Genes by Conjugation Analysis, F' Conjugation; Bacterial transduction: Analysis of Gene Transfer in Bacteria, Specialized Transduction, Generalized versus Specialized Transduction; Gene Cloning and the Polymerase Chain Reaction: Importance, Cloning Vector; Purification of DNA from Living Cells : Preparation of Total Cell DNA, Plasmid DNA and Bacteriophage DNA; Manipulation of Purified DNA: Restriction Endonucleases and ligation;  Introduction of DNA into Living Cells : Transformation, Identification of Recombinants , Introduction of Phage DNA into Bacterial and non-bacterial Cells;  Vectors for Gene Cloning: E. coli Plasmids,  M13 Bacteriophage, λ Bacteriophage; Identification of a Clone from a Gene Library: Clone Identification , The Problem of Gene Expression.

3rd Professional Year (32 credits):

Courses

Titles

Semester

Credits

 BBT302

 Metabolism II

7

3

 BBT304

 Molecular Biology II

7

3

 BBT307

 Endocrinology

7

3

 BBT350

 Immunology and Microbiology Lab

7

3

 BBT305

 Clinical Biochemistry

8

3

 BBT306

 Molecular Genetics

8

3

 BBT308

 Plant Biochemistry

8

3

 BBT203

 Biostatistics

9

3

 BBT309

 Microbial Biotechnology

9

3

 BBT310

 Basic Molecular Biology Lab

9

3

 BBT311

 Seminar II

9

2

Total Credits

32

 

BBT302: Metabolism II (3 Credits)

Structure and Membrane transport, Digestion, mobilization, and transport of Fatty acids: absorption of the dietary fatty acids in the small intestine Lipid Metabolism I: Utilization and storage of energy in lipid form, Lipid Metabolism II: Pathways of Metabolism of special Lipids such as Phospholipids, Cholesterol, Sphingolipids;  Mechanisms involved in switching the metabolism of the liver between the well-fed state and the starved state, Clinical correlations: Obesity, Respiratory distress syndrome, Atherosclerosis  and many more.

 

BBT304: Molecular Biology II (3 Credits)

The techniques of molecular biology, the molecular analysis of DNA, RNA and proteins, production of protein from cloned genes, regulation of gene expression, production of recombinant protein by prokaryotic and eukaryotic cells, fundamentals of gene expression, Studying the RNA Transcript of a Gene, Studying the Regulation of Gene Expression, introduction to genome and genomics, metagenomics, transcriptomics or functional genomics, proteomics, metabolomics and systems biology, genome analysis, restriction enzymes and site-specific DNA cleavage, restriction mapping, electrophoresis, separation and identification of genomic DNA fragments, polymerase chain reaction,  conventional PCR vs. Real-Time PCR, DNA markers, sequencing genes and genomes, applications of molecular biology, DNA profiling.

 

BBT307: Endocrinology (3 Credits) 

Endocrinology is an advanced-level course for students with sound background in biology, physiology, and metabolism. The major target of this course is to acquire an understanding of current theories of mechanisms of endocrine functions and their implications for both basic knowledge and its application in modern medicine. The course covers the endocrine system and its hormonal products, including the characterization of hormone producing cells, synthesis and modification mechanisms of the hormones, release and transport of the hormones of different chemical nature, various hormone receptors and the mechanisms of hormone action, the effects of hormones on target cells, and physiological processes, as well as the diseases caused by inappropriate hormone functions. This course will cover the general principles of endocrinology, followed by the system-based endocrinology. A minor aim is to acclimatize students with present scientific literature and the use of the vast endocrine and biomedical resources on the internet, for research.

 

BBT350: Immunology and Microbiology Lab (3 Credits)

 

This is a new laboratory course introduced to the BBT program to provide student practical knowledge in two concurrent themes: clinical immunology and applied microbiology. Clinical immunology part will concentrate on the immunological methods used to evaluate human disease and will include the theoretical basis for tests of immune function, practical laboratory application of assays based on these principles and case-based study. The learning objectives of this unit are to understand the immunological basis for infection and immunity and how these concepts are applied in the diagnostic pathology laboratory; to understand how the immune system causes and prevents disease, the use and performance of immunological tests.

The microbiological aspect of the programme concentrates on identifying the industrial requirements in the microbiological sector and provides training to meet their up-to-date requirements. This programme aims to give undergraduates a thorough training in a wide range of practical analytical techniques and ancillary skills necessary for careers in manufacturing and service industries, especially the healthcare, food, biomedical and pharmaceutical quality control sectors.

Prerequisite: BBT/MIC 303

 

BBT305: Clinical Biochemistry (3 Credits) 

This course will introduce diagnostic enzymology and the role of clinical biochemistry in evaluating diseases related to hepatic, renal, respiratory, and thyroid function and genetic disorder. An overview of the biochemistry of various diseases such as atherosclerosis, hepatitis, diabetes, rheumatoid arthritis, obesity, gout, malabsorption syndromes, acidosis and alkalosis will be given.

 

BBT306: Molecular Genetics (3 Credits)

Molecular genetics is an essential tool for studying biology. This course discusses in details the mechanisms underlying the storage, transmission and expression of heritable information in the genetic and chromosomal level of an organism. The topics that are included in this course are mutation and its repair; recombination and its role in DNA repair and genetic diversity; the concept of regulation of gene expression; developmental biology with model organism Drosophila melanogaster. At the end, this course discusses about the molecular basis of human genetics as well as epigenetic mechanisms of gene expression that is depended on the lifestyle and socio-economic environment of the individual. After completing the course, students will be able to critically evaluate experimental problems related to molecular genetics. They will also be aware of the social issues raised by the application of molecular genetics in modern society.

 

BBT308: Plant Biochemistry (3 Credits) 

This course will consider the physiological and chemical constituents of plants. The major topics of this course are photosynthesis, carbohydrates, lipids, isoprenoids and phenylpropanoids; nitrogen fixation, reduction and assimilation; the synthesis of alkaloids and general secondary compound biosynthesis. The course objectives are to acquire a good working knowledge in chemistry of important biological processes in plants and to develop the ability to readily assess current developments in plant biochemistry.

 

BBT203:  Introduction to Biostatistics (3 Credits)

This course introduces statistical concepts and analytical methods as applied to data encountered in biotechnology and biomedical sciences. It emphasizes the basic concepts of experimental design, quantitative analysis of data, and statistical inferences. Topics include probability theory and distributions; population parameters and their sample estimates; descriptive statistics for central tendency and dispersion; hypothesis testing and confidence intervals for means, variances, and proportions; the chi-square statistic; categorical data analysis; linear correlation and regression model; analysis of variance; and nonparametric methods. The course provides students a foundation to evaluate information critically to support research objectives and product claims and a better understanding of statistical design of experimental trials for biological products/devices.

 

BBT309: Microbial Biotechnology (3 Credits)

Overview of Microbial Biotechnology as an applied biological science. The scope and techniques of Microbial Biotechnology with specific examples, Important roles played by microorganisms in the treatment of solid and liquid wastes from domestic, municipal, agricultural and industrial sources, in order to reduce their potential environmental impact, Survey new developments in biomining,  Production of industrial enzymes using microorganisms and methods of enzyme immobilization, Developments in biotechnology led to the production of new kinds of vaccines, Apply biological sciences and engineering principles for manufacture of pharmaceuticals, Improvement in Agriculture using microbial molecular biotechnology principles, Strategies for Bioremediation, Biomass utilization using microbial molecular biotechnology techniques.

 

BBT310: Basic Molecular Biology Lab (3 Credits) 

The lab course is designed to introduce the students to the technical world of molecular biology. In this course the student will learn basic techniques use in molecular biology including DNA and RNA isolation, purification and detection, restriction analysis, polymerase chain reactions (PCR), expression cloning, SDS gel electrophoresis and western blotting.

 

BBT311: Seminar II  (2 Credits)

This course is designed to make students capable of making and performing several documents pertaining life science studies, research and research proposals which will be essential and beneficial for their current studies and future career. Through this course, students will be able to perform presentations and different types of scientific papers compatible with the world class recognized standards and formats.

4th Professional Year (36 credits):

 Courses

Titles

Semester

Credits

 BBT401

 Cell Biology

10

3

 BBT404

 Immunogenetics and Clinical   Immunology

10

3

 BBT406

 Human Nutrition

10

3

 BBT408

 Oncology and Virology

10

3

 BBT402

 Chemistry of Natural Products

11

3

 BBT403

 Plant Biotechnology

11

3

 BBT450

 Molecular Diagnostic Lab

11

3

 BBT499

 Project

11

4

 BBT405

 Bioinformatics

12

3

 BBT410

 Neurochemistry

12

3

 BBT412

 Biochemistry of Drugs

12

3

 BBT491

 Viva-Voice

12

2

Total Credits

36

 

BBT401: Cell Biology (3 Credits)

The cell is a fascinating, complex, and dynamic unit that is constantly interacting with the surrounding environment and making active decisions, by an enormous number of biochemical and biophysical process. A sound knowledge of cellular biochemistry is required to understand the diverse cellular components  (structure  and  function)  at  a  molecular  level  that  compose  multicellular organisms. Cellular Biochemistry forms the core of basic scientific investigations and current bio-medical research. After the completion of the course, the students will be able to apply the general principles taught in the course towards understanding an area of cell biology not covered in the course. Students will also be capable of analyze primary research literature in the field of cell biology after successful completion of this course. Furthermore, skills and knowledge from this course will be a great advantage for the students' future research carrier.

 

 

BBT404: Immunogenetics and Clinical Immunology (3 Credits)                                  

This course will enable understanding of the genetic aspects of the immune response and the role of the immune system in health and disease. Genetics of immune recognition molecules and its   knowledge in research and therapy will be discussed. Current experimental   approaches in immunology including production of monoclonal antibodies,   antibody engineering and their application are covered. This course will provide understanding of how excessive, inappropriate and defective immune responses can lead to hypersensitivity reactions, autoimmune and    immunodeficiency diseases. Topics of current immunological interest including immune tolerance, transplantation, vaccines and tumor immunology will be studied.

Prerequisite: BBT/MIC 303

 

BBT406: Human Nutrition (3 Credits)                                                                            

This course is intended for 4th year under-graduate students and has already completed BBT 208: Nutrition. Course will provide in-depth knowledge of the physiological requirements and functions of macro- and micro-nutrients that are determinants of health and diseases in human populations. Upon completion of the course, you will be able to do the following: i) Comprehensive coverage of the fundamentals of nutrition and nutrition therapy from introductory nutrition course. ii) Present current evidence for the role of key nutrients in the prevention of chronic diseases and, iv) Discuss major nutrition-related diseases in a global context.

Prerequisite: BBT208

 

BBT408: Oncology and Virology  (3 Credits)

This course is divided into two sections. The oncology section gives the epidemiology, molecular biology, Metastasis: Pathways and mechanism; and Carcinogenic agents and their cellular interactions and immunology of cancer. Types of cancers, their advanced diagnosis and treatments are covered. The virology section introduces an overview of virology that includes the nomenclature and taxonomy, structure and propagation, effect of animal viruses on host cell, pathogenesis, prevention and control of viral infection.

 

BBT402: Chemistry of Natural Products  (3 Credits)

Natural Products Chemistry is an advanced-level course in biochemistry. The goal during the course is to provide a basic knowledge and understanding on the chemical nature of secondary metabolites and the emerging trend around it to improve their properties in order to increase their biological or commercial utilization for the well-being of mankind. The course starts by exploring the historical and contemporary role of natural products in health care and commerce. The classification of natural products according to their biosynthetic origins, their chemical properties and synthetic pathway of key natural products will be discussed. A special emphasis will be placed on how chemical structure affects the physiological function of various natural products. These "structure activity relationships" help us learn about the interaction of small molecules in living systems and pharmacology of drugs.

 

BBT403: Plant Biotechnology  (3 Credits)                                                                      

This course introduces students to advanced biotechnological concepts, and prepares them for independent research in plant biotechnology. It is structured to meet the interests of all Plant Biotechnologists within the scope of expertise available in Bangladesh. During the course the emphasis is placed on four important facts of science: i) Gaining the necessary knowledge base in plant biotechnology; ii) Gaining expertise in a wide range of practical and cognitive skills, iii) The development of professional scientific methodology and ethics and iv) Developing a professional attitude.

 

BBT450: Molecular Diagnostic Lab (4 Credits)                                                               

The principal aim of this course is to introduce the students modern techniques of molecular biology used in clinical diagnosis. The course will emphasise the importance on molecular diagnostic and clinical applications in light of the process of diagnosis and the diagnostic importance of pathology and genetics.

 

BBT405 Bioinformatics  (3 Credits)

Bioinformatics involves the application of computational methods in order to address problems in molecular biology. This course will provide a graduate introduction to algorithms and their applications in bioinformatics. Topics in molecular biology that will motivate the algorithmic content of the course include: sequence alignment, phylogenetic tree reconstruction, prediction of RNA and protein structure, gene finding and sequence annotation, gene expression, and biomolecular computing. This is an interdisciplinary course, and the goal is to involve students who have strong background in molecular biology (such as students in the genetics, microbiology and biochemistry graduate program) familiar with free biological data base and software in internet. Practical work will familiarize students with biological data and tools for understanding this data and will help students gain a solid understanding of utilizing IT in everyday biological research. Some assignments will involve use and extension of software tools, and others will involve written studies of algorithms and their analysis.

BIO210 is the pre-requisite for other disciplinary students for this course.

 

BBT410: Neurochemistry (3 Credits)                                                                              

This Neurochemistry course provides a broad introduction to the mammalian nervous system with a particular focus on the structure and function of the human brain. Neurons have a special cellular chemistry related to their ability to send and receive chemical signals. The course comprises the biochemistry of the nervous system; neurotransmitter synthesis and metabolic mechanisms at the synapse, release and re-uptake/degradation of classical neurotransmitters and peptide transmitters. Receptors for neurotransmitters and their ligands will be described from a chemical-pharmacological point of view and the relevance of these molecules and their interactions for development of tolerance, super-sensitivity and long-term potentiation will be discussed. Different chemical signalling pathways and their connections to developmental malfunctions will also be included in this course. This advanced-level undergraduate course put emphasis on human neurological diseases that includes the basic knowledge of neurobiology, molecular biology, biochemistry, and cell biology. After completion of this course, the students will have sufficient knowledge about cellular and molecular neuroscience.

 

BBT412: Biochemistry of Drugs  (3 Credits)                                                                   

This course is designed to give a detailed knowledge on prescription and non-prescription drugs which include broad classification and features of drugs with specific examples. Pharmacokinetics, molecular mechanism of drug action, drug design, drug targeting and pharmacogenomics are included.

 

BBT491: Viva-Voce  (2 Credits)

Students will face viva before the viva board and answer comprehensive questions on the entire 4 year syllabus of studies. They will also be tested on their ability to answer analytical case study questions. Additionally they are tested on their ability to relate information from various aspects of Biochemistry.

Course Information

BBT Taught Courses

Students have to complete or take these courses during the program. Students should regularly monitor their progress in taught courses and realistically assess the likelihood of achieving at a level which is consistent with their academic and personal goals. Weak performance (B or lower) in taught courses may indicate a need to re-evaluate commitment and interest. Students with questions and concerns are encouraged to talk to the respective faculty members.

Taught Courses: (81 credits)

 

Course ID

Titles

Credits

 BBT101

 Introduction to Biochemistry & Biotechnology

3

 BBT201

 Biophysical Chemistry

3

 BBT202

 Bio-organic Chemistry I

3

 BBT203

 Biostatistics

3

 BBT204

 Molecular Biology I

3

 BBT205

 Metabolism I

3

 BBT206

 Proteins & Enzymes

3

 BBT207

 Human Physiology

3

 BBT208

 Introduction to Nutrition

3

 BBT301

 Bio-organic Chemistry II

3

 BBT302

 Metabolism II

3

 BBT303

 Basic Immunology

3

 BBT304

 Molecular Biology II

3

 BBT305

 Clinical Biochemistry

3

 BBT306

 Molecular Genetics

3

 BBT307

 Endocrinology

3

 BBT308

 Plant Biochemistry

3

 BBT309

 Microbial Biotechnology

3

 BBT401

 Cell Biology

3

 BBT402

 Chemistry of Natural Products

3

 BBT403

 Plant Biotechnology

3

 BBT404

 Immunogenetics and Clinical Immunology

3

 BBT405

 Bioinformatics

3

 BBT406

 Human Nutrition

3

 BBT408

 Oncology & Virology

3

 BBT410

 Neurochemistry

3

 BBT412

 Biochemistry of Drugs

3

 

BBT101: Introduction to Biochemistry and Biotechnology                                          3 Credits

This course introduces history, scope and future of Biochemistry and biotechnology. Students learn the basic logics of living organisms, the role of bio-molecules and their interrelationship. The course provides following introductory concepts: i) define and explain the basic concepts in biochemistry; ii) various biochemical pathways; iii) define the biological macromolecules and their subunits; iv) basic applied concepts in biochemistry to biotechnology; v) explain the underlying concepts in biotechnology; and vi) relate the biochemical properties and their principles as tools of biotechnology.

 

BBT201: Biophysical Chemistry                                                                                        3 Credits

Thermodynamics - First law, Second law and Introduction, definitions, Thermodynamic terms and basic concepts; Thermochemistry, Exothermic and endothermic reactions, standard enthalpy of formation, thermochemical equations; The nature of chemical equilibrium, law of mass action, equilibrium constant,  relationship between ∆G and Keq, effect of temperature and pressure, Le Chatelier’s principle,, Chemical Kinetics and it Definition, reaction rate, rate laws, order reactions, molecularity of a reaction, pseudo first order reaction, half-life, Catalysis, Photochemistry and Spetrophotometry, Transmittance and absorbance, Beer-Lambert law, Properties of liquids, Acids and bases.

 

BBT202: Bio-organic Chemistry I  (3 Credits)

This course is a comprehensive introduction in fundamental aspects of biological chemistry, for freshmen students. Knowledge of structure, functionality and reactivity of the organic molecules is vital for understanding the mechanism of numerous biological processes and biochemical reactions. This course provides a foundation of organic chemistry, i.e. the understanding of structure, properties, interactions, transformations and nomenclature of organic compounds. The Students attending the course will be able to recognize the major functional groups, write systematic names, draw accurate structures, correlate molecular structure with physical and chemical properties, categorize reactions by type, write or recognize essential reaction mechanisms, and recognize the structures and functions of the main classes of biomolecules.

 

BBT203:  Introduction to Biostatistics (3 Credits)

This course introduces statistical concepts and analytical methods as applied to data encountered in biotechnology and biomedical sciences. It emphasizes the basic concepts of experimental design, quantitative analysis of data, and statistical inferences. Topics include probability theory and distributions; population parameters and their sample estimates; descriptive statistics for central tendency and dispersion; hypothesis testing and confidence intervals for means, variances, and proportions; the chi-square statistic; categorical data analysis; linear correlation and regression model; analysis of variance; and nonparametric methods. The course provides students a foundation to evaluate information critically to support research objectives and product claims and a better understanding of statistical design of experimental trials for biological products/devices.

 

BBT204: Molecular Biology I  (3 Credits)

Important historical developments in genetics, particularly the contributions of Mendel, and Watson & Crick; and important research advances; Analysis of genetic problems using Punnett squares to illustrate Mendelian principles; Chromosome basis of inheritance, sex determination and sex linkage; types of chromosomal aberrations and their consequences; molecular genetics, gene function, the structure of genetic material; the organization of DNA in chromosomes; structure and replication of DNA, concepts of protein synthesis, gene expression, mutations, and genetic engineering;   transcription and the structural and functional features of the transcripts; genetic code and the translation of the genetic message.

 

BBT205: Metabolism I  (3 Credits) 

Bioenergetics and thermodynamics; The glycolytic pathway, two phases of glycolysis, Secondary pathways of glucose oxidation; The citric acid cycle: Steps and reactions involved, Metabolic fates of Amino groups, enzymatic degradation of the dietary proteins to amino acids, oxidative phosphorylation and photophosphorylation, The chemiosmotic model; regulation of oxidative phosphorylation by cellular energy needs, Gluconeogenesis and Reciprocal regulation of gluconeogenesis and glycolysis, Nitrogen metabolism, Integration and hormonal regulation of mammalian metabolism.

                                                                                                                                                           

BBT206: Proteins and Enzymes (3 Credits)

The objective of this course is to provide understanding on protein structure, properties and their most important functions. Key concepts related to this course are studying properties of amino acids and peptides, reaction and analysis of amino acids, different structural level of organization of proteins with specific examples, how protein interact with other molecules related to their function and different analytical techniques use in protein chemistry. Studying enzymes and its classification, enzyme kinetics, enzymes mechanism of action, enzyme inhibition, regulation, and reaction mechanism of some enzymes and clinical, diagnostic and industrial application of enzymes are also key notions relation to this course. This course will be useful for future studies in biochemistry, microbiology, molecular and cellular biology, biotechnology, pharmaceutical and medically related fields.

 

BBT207: Human Physiology (3 Credits) 

Physiology is the study of how living organism functions. The main theme of human physiology is the molecular and cellular interaction to maintain the constant internal environment, i.e. homeostasis. This course commences with the principles of physiology, which is followed by an elaborate discussion of molecular-cellular physiology with a specific focus on neural and endocrine control and integration of homeostasis. Individual organ systems, including musculoskeletal, circulatory, respiratory, digestive, urinary, and reproductive systems also given emphasis for a complete understanding that how human body functions.

 

BBT208: Introduction to Nutrition (3 Credits) 

This course is intended for 2nd Year under-graduate students going to complete organic chemistry, biochemistry, molecular biology and physiology. Course will provide an integrated overview of the physiological requirements and functions of macro- and micro-nutrients that are determinants of health and diseases in human populations. The course provides an overview of the major macro- and micro-nutrients relevant to human health. Discuss the scientific rationale for defining nutritional requirements in healthy individuals and populations, with reference to specific conditions such as pregnancy, lactation, and older age. The topics will also cover current evidence for the role of key nutrients in the prevention of chronic diseases. Discuss major nutrition-related diseases in a global context.

 

BBT301: Bio-organic Chemistry II (3 Credits)

The course starts with a review of organic functional groups structure & functions and stereochemistry. Later, the discussion will continue with the structures of small bio-molecules, e.g. carbohydrates, amino acids, nucleotides, and lipids. Next, the formation of large bio-molecules from these building blocks is described in terms of the RNA world hypothesis.  The chemistry behind both the formation and degradation of these compounds both in vitro and in vivo in the modern world will be covered through study of the properties of acetals, phosphate esters and amides with emphasis on learning about complex biological systems from simpler chemical ones. This course will help the students to understand complex biological interactions in terms of basic organic chemistry.

 

BBT302: Metabolism II (3 Credits)

Structure and Membrane transport, Digestion, mobilization, and transport of Fatty acids: absorption of the dietary fatty acids in the small intestine Lipid Metabolism I: Utilization and storage of energy in lipid form, Lipid Metabolism II: Pathways of Metabolism of special Lipids such as Phospholipids, Cholesterol, Sphingolipids;  Mechanisms involved in switching the metabolism of the liver between the well-fed state and the starved state, Clinical correlations: Obesity, Respiratory distress syndrome, Atherosclerosis  and many more.

 

BBT303: Basic Immunology (3 Credits)

The purpose of this course is to provide a basic knowledge of immunology. This course will provide in-depth understanding the cells, molecules and organs of the immune system and how they work   together to protect us from pathogen. The principal focus of the course will be on studying structural features of the components of the immune system and their functions, innate and adaptive branches of both humoral and cellular responses of the immune system. The course will also assign emphasis on learning the major mechanisms by which immune cells protect us from different types of pathogens or from cancer cells, how immune cells detect the presence of pathogens and cancer cells, processes that lead to the elimination of pathogens. Studying the structure and function of key immune recognition molecules including antigens, antibodies, antigen receptors, MHC proteins, cytokines are covered. The course will introduce some immunological assays to detect antigen-antibody interactions.

 

BBT304: Molecular Biology II  (3 Credits)

The techniques of molecular biology, the molecular analysis of DNA, RNA and proteins, production of protein from cloned genes, regulation of gene expression, production of recombinant protein by prokaryotic and eukaryotic cells, fundamentals of gene expression, Studying the RNA Transcript of a Gene, Studying the Regulation of Gene Expression, introduction to genome and genomics, metagenomics, transcriptomics or functional genomics, proteomics, metabolomics and systems biology, genome analysis, restriction enzymes and site-specific DNA cleavage, restriction mapping, electrophoresis, separation and identification of genomic DNA fragments, polymerase chain reaction,  conventional PCR vs. Real-Time PCR, DNA markers, sequencing genes and genomes, applications of molecular biology, DNA profiling.                                                            

 

BBT305: Clinical Biochemistry (3 Credits) 

This course will introduce diagnostic enzymology and the role of clinical biochemistry in evaluating diseases related to hepatic, renal, respiratory, and thyroid function and genetic disorder. An overview of the biochemistry of various diseases such as atherosclerosis, hepatitis, diabetes, rheumatoid arthritis, obesity, gout, malabsorption syndromes, acidosis and alkalosis will be given.

 

BBT306: Molecular Genetics (3 Credits)

Molecular genetics is an essential tool for studying biology. This course discusses in details the mechanisms underlying the storage, transmission and expression of heritable information in the genetic and chromosomal level of an organism. The topics that are included in this course are mutation and its repair; recombination and its role in DNA repair and genetic diversity; the concept of regulation of gene expression; developmental biology with model organism Drosophila melanogaster. At the end, this course discusses about the molecular basis of human genetics as well as epigenetic mechanisms of gene expression that is depended on the lifestyle and socio-economic environment of the individual. After completing the course, students will be able to critically evaluate experimental problems related to molecular genetics. They will also be aware of the social issues raised by the application of molecular genetics in modern society.

 

BBT307: Endocrinology (3 Credits) 

Endocrinology is an advanced-level course for students with sound background in biology, physiology, and metabolism. The major target of this course is to acquire an understanding of current theories of mechanisms of endocrine functions and their implications for both basic knowledge and its application in modern medicine. The course covers the endocrine system and its hormonal products, including the characterization of hormone producing cells, synthesis and modification mechanisms of the hormones, release and transport of the hormones of different chemical nature, various hormone receptors and the mechanisms of hormone action, the effects of hormones on target cells, and physiological processes, as well as the diseases caused by inappropriate hormone functions. This course will cover the general principles of endocrinology, followed by the system-based endocrinology. A minor aim is to acclimatize students with present scientific literature and the use of the vast endocrine and biomedical resources on the internet, for research.

 

BBT308: Plant Biochemistry  (3 Credits) 

This course will consider the physiological and chemical constituents of plants. The major topics of this course are photosynthesis, carbohydrates, lipids, isoprenoids and phenylpropanoids; nitrogen fixation, reduction and assimilation; the synthesis of alkaloids and general secondary compound biosynthesis. The course objectives are to acquire a good working knowledge in chemistry of important biological processes in plants and to develop the ability to readily assess current developments in plant biochemistry.

 

BBT309: Microbial Biotechnology (3 Credits)

Overview of Microbial Biotechnology as an applied biological science. The scope and techniques of Microbial Biotechnology with specific examples, Important roles played by microorganisms in the treatment of solid and liquid wastes from domestic, municipal, agricultural and industrial sources, in order to reduce their potential environmental impact, Survey new developments in biomining,  Production of industrial enzymes using microorganisms and methods of enzyme immobilization, Developments in biotechnology led to the production of new kinds of vaccines, Apply biological sciences and engineering principles for manufacture of pharmaceuticals, Improvement in Agriculture using microbial molecular biotechnology principles, Strategies for Bioremediation, Biomass utilization using microbial molecular biotechnology techniques.

 

BBT401: Cell Biology  (3 Credits)

The cell is a fascinating, complex, and dynamic unit that is constantly interacting with the surrounding environment and making active decisions, by an enormous number of biochemical and biophysical process. A sound knowledge of cellular biochemistry is required to understand the diverse cellular components  (structure  and  function)  at  a  molecular  level  that  compose  multicellular organisms. Cellular Biochemistry forms the core of basic scientific investigations and current bio-medical research. After the completion of the course, the students will be able to apply the general principles taught in the course towards understanding an area of cell biology not covered in the course. Students will also be capable of analyze primary research literature in the field of cell biology after successful completion of this course. Furthermore, skills and knowledge from this course will be a great advantage for the students' future research carrier.

 

BBT402: Chemistry of Natural Products (3 Credits)

Natural Products Chemistry is an advanced-level course in biochemistry. The goal during the course is to provide a basic knowledge and understanding on the chemical nature of secondary metabolites and the emerging trend around it to improve their properties in order to increase their biological or commercial utilization for the well-being of mankind. The course starts by exploring the historical and contemporary role of natural products in health care and commerce. The classification of natural products according to their biosynthetic origins, their chemical properties and synthetic pathway of key natural products will be discussed. A special emphasis will be placed on how chemical structure affects the physiological function of various natural products. These "structure activity relationships" help us learn about the interaction of small molecules in living systems and pharmacology of drugs.

 

BBT403: Plant Biotechnology   (3 Credits)                                                                     

This course introduces students to advanced biotechnological concepts, and prepares them for independent research in plant biotechnology. It is structured to meet the interests of all Plant Biotechnologists within the scope of expertise available in Bangladesh. During the course the emphasis is placed on four important facts of science: i) Gaining the necessary knowledge base in plant biotechnology; ii) Gaining expertise in a wide range of practical and cognitive skills, iii) The development of professional scientific methodology and ethics and iv) Developing a professional attitude.

 

BBT404: Immunogenetics and Clinical Immunology  (3 Credits)                                 

This course will enable understanding of the genetic aspects of the immune response and the role of the immune system in health and disease. Genetics of immune recognition molecules and its   knowledge in research and therapy will be discussed. Current experimental   approaches in immunology including production of monoclonal antibodies,   antibody engineering and their application are covered. This course will provide understanding of how excessive, inappropriate and defective immune responses can lead to hypersensitivity reactions, autoimmune and    immunodeficiency diseases. Topics of current immunological interest including immune tolerance, transplantation, vaccines and tumor immunology will be studied.

Prerequisite: BBT/MIC 303

 

BBT405 Bioinformatics (3 Credits)

Bioinformatics involves the application of computational methods in order to address problems in molecular biology. This course will provide a graduate introduction to algorithms and their applications in bioinformatics. Topics in molecular biology that will motivate the algorithmic content of the course include: sequence alignment, phylogenetic tree reconstruction, prediction of RNA and protein structure, gene finding and sequence annotation, gene expression, and biomolecular computing. This is an interdisciplinary course, and the goal is to involve students who have strong background in molecular biology (such as students in the genetics, microbiology and biochemistry graduate program) familiar with free biological data base and software in internet. Practical work will familiarize students with biological data and tools for understanding this data and will help students gain a solid understanding of utilizing IT in everyday biological research. Some assignments will involve use and extension of software tools, and others will involve written studies of algorithms and their analysis.

BIO210 is the pre-requisite for other disciplinary students for this course.

 

BBT406: Human Nutrition (3 Credits)                                                                            

This course is intended for 4th year under-graduate students and has already completed BBT 208: Nutrition. Course will provide in-depth knowledge of the physiological requirements and functions of macro- and micro-nutrients that are determinants of health and diseases in human populations. Upon completion of the course, you will be able to do the following: i) Comprehensive coverage of the fundamentals of nutrition and nutrition therapy from introductory nutrition course. ii) Present current evidence for the role of key nutrients in the prevention of chronic diseases and, iv) Discuss major nutrition-related diseases in a global context.

Prerequisite: BBT208

 

BBT408: Oncology and Virology (3 Credits)

This course is divided into two sections. The oncology section gives the epidemiology, molecular biology, Metastasis: Pathways and mechanism; and Carcinogenic agents and their cellular interactions and immunology of cancer. Types of cancers, their advanced diagnosis and treatments are covered. The virology section introduces an overview of virology that includes the nomenclature and taxonomy, structure and propagation, effect of animal viruses on host cell, pathogenesis, prevention and control of viral infection.

 

BBT410: Neurochemistry (3 Credits)                                                                              

This Neurochemistry course provides a broad introduction to the mammalian nervous system with a particular focus on the structure and function of the human brain. Neurons have a special cellular chemistry related to their ability to send and receive chemical signals. The course comprises the biochemistry of the nervous system; neurotransmitter synthesis and metabolic mechanisms at the synapse, release and re-uptake/degradation of classical neurotransmitters and peptide transmitters. Receptors for neurotransmitters and their ligands will be described from a chemical-pharmacological point of view and the relevance of these molecules and their interactions for development of tolerance, super-sensitivity and long-term potentiation will be discussed. Different chemical signalling pathways and their connections to developmental malfunctions will also be included in this course. This advanced-level undergraduate course put emphasis on human neurological diseases that includes the basic knowledge of neurobiology, molecular biology, biochemistry, and cell biology. After completion of this course, the students will have sufficient knowledge about cellular and molecular neuroscience.

 

BBT412: Biochemistry of Drugs  (3 Credits)                                                                   

This course is designed to give a detailed knowledge on prescription and non-prescription drugs which include broad classification and features of drugs with specific examples. Pharmacokinetics, molecular mechanism of drug action, drug design, drug targeting and pharmacogenomics are included.

BBT Laboratory & Seminar Courses:

During four professional years students have to attend five (5) laboratory courses where they will get practical experiences about six (6) mainstreams of biological fields: Biochemistry, Immunology, Microbiology, Molecular Biology, Nutrition and Organic chemistry. These labs along with the seminar courses have designed to guide the students to conduct their undergraduate project. Furthermore these courses will develop the student’s ability to correlate between the theoretical with practical knowledge.

Laboratory and Seminar Courses: 25 credits

 

Course ID

Titles

Credits

 BBT 109

 Introductory organic chemistry and Microbiology lab

3

 BBT 209

 Biochemistry and Nutrition Lab

3

 BBT310

 Basic Molecular Biology Lab

3

 BBT350

 Immunology and Microbiology Lab

3

 BBT450

 Molecular Diagnostic Lab

3

 BBT499

 Project

4

 BBT210

 Seminar I

2

 BBT311

 Seminar II

2

 BBT491

 Viva-Voce

2

 

BBT109: Introductory organic chemistry and Microbiology Lab (3 Credits)

The basic idea of a biochemistry and microbiology laboratory will be provided in this course. The students will get practical experiences on the detection of an unknown organic compound based on their physical and chemical properties. Emphasis will be given on the nature of different biochemical solution and how to prepare them accurately. Moreover students will also get basic idea how to detect specific organic compound present in biological sample. In the microbiology section the basic laboratory skill will be discussed and student will learn the basic techniques to detect and isolate microorganisms from food and water samples.

 

BBT209: Biochemistry and Nutrition Lab (3 Credits)

This laboratory course deals with two broad biological fields: biochemistry and nutrition. Main objective of the biochemistry part is to bring experience in solving practical problems in biochemistry laboratory, to acquire applicable skills and to teach students to derive conclusions from experiments. Biochemistry part also demonstrates methods of clinical biochemistry and their significance for diagnosis of diseases. The nutrition part is targeted at manufacturers, food technologists and quality control managers in the food industry and provides “hands-on” practical training to such personnel in analyzing accurate nutritional value in food samples using international standard methods. At the end of the course, participants should be able to use the various methods presented in the analysis of the nutritional content in their food products for quality control purpose.

 

BBT310: Basic Molecular Biology Lab (3 Credits) 

The lab course is designed to introduce the students to the technical world of molecular biology. In this course the student will learn basic techniques use in molecular biology including DNA and RNA isolation, purification and detection, restriction analysis, polymerase chain reactions (PCR), expression cloning, SDS gel electrophoresis and western blotting.

 

BBT350: Immunology and Microbiology Lab (3 Credits)

This is a new laboratory course introduced to the BBT program to provide student practical knowledge in two concurrent themes: clinical immunology and applied microbiology. Clinical immunology part will concentrate on the immunological methods used to evaluate human disease and will include the theoretical basis for tests of immune function, practical laboratory application of assays based on these principles and case-based study. The learning objectives of this unit are to understand the immunological basis for infection and immunity and how these concepts are applied in the diagnostic pathology laboratory; to understand how the immune system causes and prevents disease, the use and performance of immunological tests.The microbiological aspect of the programme concentrates on identifying the industrial requirements in the microbiological sector and provides training to meet their up-to-date requirements. This programme aims to give undergraduates a thorough training in a wide range of practical analytical techniques and ancillary skills necessary for careers in manufacturing and service industries, especially the healthcare, food, biomedical and pharmaceutical quality control sectors.

Prerequisite: BBT/MIC 303

 

BBT450: Molecular Diagnostic Lab (4 Credits)                                                               

The principal aim of this course is to introduce the students modern techniques of molecular biology used in clinical diagnosis. The course will emphasise the importance on molecular diagnostic and clinical applications in light of the process of diagnosis and the diagnostic importance of pathology and genetics.

 

BBT210: Seminar I  (2 Credits) 

The objective of this course is to give students the confidence to make oral presentations before small and large audiences and to train students in basic skills in preparing and delivering audio visual presentations, including audience interaction and effective use of visual aids. Students will prepare and present on various topics throughout the semester, which will be evaluated by the faculty. They will also be expected to answer questions and tackle problems during the presentation.

 

BBT311: Seminar II (2 Credits)

This course is designed to make students capable of making and performing several documents pertaining life science studies, research and research proposals which will be essential and beneficial for their current studies and future career. Through this course, students will be able to perform presentations and different types of scientific papers compatible with the world class recognized standards and formats.

 

BBT491: Viva-Voce (2 Credits)

Students will face viva before the viva board and answer comprehensive questions on the entire 4 year syllabus of studies. They will also be tested on their ability to answer analytical case study questions. Additionally they are tested on their ability to relate information from various aspects of Biochemistry.

GED Courses

General educational developments (GED) are the courses offered with the core courses. Department allows a student to choose nine courses from 16 GED courses. These 16 courses provide supports to core courses and also develop their skills in Computer literacy, English, Psychology, Sociology, Business and Marketing.

General Education Courses for the BBT undergraduate students (GED): 27 Credits

 

Course ID

Titles

Credits

 BBT102

 Basic Microbiology

3

 BBT103

 Computer and Communications

3

 BBT116

 Math for Biologists

3

 BBT211

 Physics for Biologists

3

 CHE101

 General Chemistry

3

 ENG102

 Introduction to Composition

3

 ENG103

 Intermediate Composition

3

 ENG105

 Advanced Composition

3

 MIC307

 Microbial Genetics

3

 MIC412

 Bacterial Pathogenesis

3

 PSY 101

 Introduction of Psychology

3

 SOC101

 Introduction of Sociology

3

 BUS 101

 Introductory to Business

3

 MKT 202

 Introduction to Marketing

3

 

BBT102: Basic Microbiology  (3 Credits)

Important historical developments which led to the formulation of the germ theory of disease and those discoveries that lead to the development of the science of biotechnology; historical background of the classification of microorganisms, and the techniques used to categorize them; differences between the old five-kingdom system and the modern three-domain system; structure and function of prokaryotic and eukaryotic cells; Bacterial growth curve- lag phase, exponential phase, stationary phase and death phase; archaeal diversity and life in extreme environment; survey of prokaryotic microorganisms with unusual characteristics; basic structure and characteristics of viruses, infection process with emphasis on animal viruses and bacteriophage; diversity and importance of eukaryotic microorganisms, namely protozoa, fungi and algae; nutritional requirement of microorgamisms and classification; cultivation of microorganisms in the laboratory.

 

BBT103: Computer and Communications (3 Credits)

The students in Computer and Communications will be using personal computers in their everyday activities and projects. This subject will be covering four major areas: Windows; Microsoft Office applications, the Internet (Search engine and Introduction to Bioinformatics), and Draw/Paint. The students will acquire the basics of the Windows system so that they will be able to navigate with ease through the various applications they will be using throughout their graduation. Microsoft Office contains word processing, spreadsheet, and presentation applications—software that will be critical for degree and career success. All the computers in the class have Internet access. For many of their projects, the students will be working in collaborative groups. Students will be working side-by-side to complete exercises and produce final projects. This course has been provided to student as GED course.

 

BBT116: Math for Biologists (3 Credits)

The major objective of the course is to provide a student majoring in the biological sciences a mastery of the basic concepts of mathematics of changing and explore some of its applications in related fields. The concepts of differentiation and integration of different functions including vectors and differential equations will be the major focus of this course. The emphasis will be given on analytical, numerical and graphical approach of these topics. This course has been provided to student as GED course.

 

BBT211: Physics for Biologist (3 Credits) 

This course has been design especially for biological student in order to understand the concepts and principles of physics. In this course, we will discuss conceptual and quantitative problems and questions. A comprehensive coverage of subject matter in physics is presented, including mechanics, properties of matter, wave motions, electricity, magnetism, optics and atomic and nuclear physics. The major objective of the course is to provide a student majoring in the biological sciences a mastery of the basic concepts of physics and explore some of its applications in related fields.

 

CHE101: General Chemistry  (3 Credits)

This course covers fundamental principles of chemistry. Topics include measurement, atomic and molecular structure, periodicity, chemical reactions, chemical bonding, stoichiometry, thermochemistry, Chemical Equilibrium and Kinetics, gas laws and solutions. This course is appropriate as a basic chemistry course or as a science elective for students who have science, engineering, or mathematics majors. Upon completion, students will be able to- Define chemistry as the study of matter, can apply the basic concepts in their future studies and apply safe laboratory skills to solve problems in a cooperative environment.

 

BBT307: Endocrinology (3 Credits) 

Endocrinology is an advanced-level course for students with sound background in biology, physiology, and metabolism. The major target of this course is to acquire an understanding of current theories of mechanisms of endocrine functions and their implications for both basic knowledge and its application in modern medicine. The course covers the endocrine system and its hormonal products, including the characterization of hormone producing cells, synthesis and modification mechanisms of the hormones, release and transport of the hormones of different chemical nature, various hormone receptors and the mechanisms of hormone action, the effects of hormones on target cells, and physiological processes, as well as the diseases caused by inappropriate hormone functions. This course will cover the general principles of endocrinology, followed by the system-based endocrinology. A minor aim is to acclimatize students with present scientific literature and the use of the vast endocrine and biomedical resources on the internet, for research.

 

MIC412: Bacterial Pathogenesis  (3 Credits)

Principles of bacterial cell biology, including genome plasticity, mobile genetic elements, intracellular signaling, membrane biogenesis; concepts of prokaryotic cell signaling including chemotaxis/motility, cell-cell signaling (quorum sensing, biofilms); bacterial virulence strategies, such as LPS synthesis and expression of carbohydrate receptors; bacterial exploitation of host cell biology: mucosal cell entry, transcytosis, intracellular trafficking and survival, Role of bacterial community with respect to intestinal flora and health, key players of host cell defense: innate receptors, innate effectors (collectins, defensins, sIgA mucus) mechanisms of action of antibiotics and resistance mechanism, integrons, plasmids and efflux pumps , protein secretion systems, pathogenicity islands, bacterial adhesion, immune evasion strategies and novel antibiotics/phage therapy.

Career

Career in Biochemistry/Biotechnology

What is Biochemistry and Biotechnology?

Biochemistry explores the chemistry of life. A multidisciplinary science, it draws on chemistry, microbiology, molecular biology and molecular genetics in the study of living organisms and how they work at the molecular level. Biochemical research has led to improvements in the quality of food products and production processes, it has resulted in better environmental monitoring and protection, and it has produced advances in disease diagnosis, surveillance, treatment and prevention.

Biotechonology, the application of biochemistry to industry, is one of the fastest-growing sectors of the global economy. Growth in biochemical science and biotechnology is creating opportunities for university graduates in research institutes and the pharmaceutical and biotechnology industries.

 

Where does Biochemist and biotechnologist work and with whom?

Biochemists and Biotechnologists often have the opportunity to work in teams on research projects (where they report to a supervisor), or they are assigned individual tasks in modern, well-equipped labs. The work schedule is generally regular with occasional opportunities for overtime when a project deadline is approaching. Biochemists, who opt for the teaching route, whether at the high school, college or university level, put in hours outside the classroom to be well prepared for their students.

There are plenty of job openings for Biochemists and Biotechnologists interested in carrying out applied research for private companies in health, nutra- & beauty care, chemical manufacturing, food and drink production, medical instruments and pharmaceutical development. Even those without advanced degrees should also be able to find employment in these sectors.

The government funds many biochemical research projects through the Food and Drug Administration, the Environmental Protection Agency and the National Institutes of Health. Positions for biochemists within these agencies will depend on levels of federal funding. Other settings in which biochemists will find employment include hospitals, public health laboratories, cancer research institutes, environmental pollution control and public health offices. 

What kinds of career paths are there?

A degree in biotechnology is not a one way ticket into a lab coat. An education in biotechnology can set you up for a wide variety of careers including management, marketing, and of course, laboratory science. Below you will find a comprehensive view of some career potential of a biochemistry and biotechnology undergraduate.

  • Bioinformatician
  • Biomedical Engineer
  • Biotechnology Laboratory Assistant
  • Biotechnology Research Associate
  • Clinical Research Associate
  • Forensic Lab Scientists
  • Quality Control Analyst
  • Quality Control Engineer
  • Senior Research Scientist
  • Validation Scientist
  • Biotechnology / Pharmaceutical Marketing


How the Biochemistry and Biotechnology programme in North South University can help to build your career?

Biochemistry of Biotechnology undergraduate programme of the North South University are highly regarded among renowned universities and employers in both Bangladesh and abroad. A Biochemistry and Biotechnology degree from NSU is an excellent qualification for securing your future career in a diverse range of industries and employment sectors. Whether you have a clear idea of where your future aspirations lie or want to consider the broad range of opportunities available once you have a NSU degree, our Careers and Employability Service consultation by the department faculties can help you to achieve your goal.

Advances in the biosciences are having a profound impact on our daily lives in areas from human health to conservation. Biotechnology, biological pharmaceuticals, and personalised medicine are key growth areas in the health sector. Environmental remediation, climate change and related themes pose multi-faceted challenges for the coming decades. Expert knowledge in the life sciences will be in high demand for the foreseeable future, with bright prospects for exciting and rewarding careers in research, teaching, industry, the government health service and the public sector.

A substantial part of our undergraduates choose to take a further degree, a Masters in NSU or PhD in abroad from prestigious international institutes. For many career paths, a further degree is an essential stepping-stone, including (but not limited to) careers in research. Our undergraduates and are highly sought after by universities around the world, many stay in Bangladesh and join in different prestigious research groups in ICDDR, B, BCSIR and so on.

In order to help you build an attractive CV, undergraduates project and graduate thesis from the Department of Biochemistry and Microbiology can help to accommodate an internship in a research (departmental or external) laboratory or in a company.

The University and the Department of Biochemistry and Microbiology provide a range of services to support you in finding a career and to build a CV that stands out from the crowd. The faculty advisers hold drop-in sessions, discussing with you how to prepare a CV and cover letters, the graduate application process and how to explore possible career paths. Furthermore, the School of Life Sciences is planning to hold an annual Biosciences Careers Fair, brings employers from life sciences sector to our NSU for networking and discussions.