BPharm (4 years)

Overview

The aim of the introduction of the pharmacy program in North South University is to prepare students to be the most competent, responsible, and caring pharmacist or pharmaceutical scientist. It is designed to produce the skilled and efficient professionals to manage pharmaceutical industries, hospital pharmacy, community pharmacy services and other government body related to health services and research organizations. The curriculum offered is very competitive with national and international universities, students following successful completion of this program will be able to conduct higher studies and work at home and abroad without any difficulties. 

The faculties of the department are renowned professors with bright academic and research aptitude which will ensure the quality education, generate profound research and analytical skill. 

The Bachelor of Pharmacy is 4 years degree program. The total credit offered is 155. The curriculum include sound knowledge on organic and inorganic chemistry, physical chemistry, analytical chemistry, biochemistry, medicinal chemistry, physiology, and anatomy, pharmacology, hospital and clinical pharmacology, community pharmacy, toxicology, pharmacognosy, bio pharmaceutics, pharmaceutical engineering, pharmaceutical marketing, pharmacy law etc. 

The student will conduct advanced research on drug discovery, drug bioavailability, drug formulation, pharmaceutical marketing, molecular biology, pharmacology, analytical chemistry etc.

Curriculum

Requirements for the Bachelor of Pharmacy (BPharm) program are:

1st Professional Year (40 credits):

Courses

Titles  

Credits

1st Year 1st Semester

PHR 110

Introduction to Pharmacy

2

PHR 111

Communication & Computer Application in Pharmaceutical Sciences

3

PHR 112

Statistics in Pharmaceutical Sciences

3

PHR 113

Pharmacognosy

3

PHR 113L

Pharmacognosy Lab

1

PHR 114

Organic Pharmacy-I

3

PHR 114L

Organic Pharmacy Lab-I

1

PHR 115

Pharmaceutical calculations

2

Total Credits

18

1st Year 2nd Semester

ENG 103

Intermediate Composition

3

PHR 120

Inorganic Pharmacy

3

PHR 120L

Inorganic Pharmacy-Lab

1

PHR 121

Human Physiology-I

3

PHR 122

Organic Pharmacy -II

3

PHR 122L

Organic Pharmacy Lab-II

1

PHR 123

Physical Pharmacy-I

3

PHR 124

Pharmaceutical Microbiology-I

3

PHR 124L

Pharmaceutical Microbiology-Lab-I

1

PHR 100

Viva voce

1

Total Credits

22

 


2nd Professional Year (43 credits):

Courses

Titles  

Credits

2nd Year 1st Semester

PHR 210

Physical Pharmacy-II

3

PHR 210L

Physical Pharmacy Lab

1

PHR 211

Human Physiology-II

3

PHR 211L

Human Physiology Lab

1

PHR 212

Pharmaceutical Technology-I

3

PHR 212L

Pharmaceutical Technology Lab-I

1

PHR 213

Biochemistry & Cell Biology

3

PHR 214

Pharmacology & Clinical Pharmacy-I

3

PHR 215

Medicinal Chemistry-I

3

Total Credits

21

2nd Year 2nd Semester

PHR 215L

Medicinal Chemistry Lab-I

1

PHR 220

Human Physiology-III

3

PHR 221

Pharmaceutical Technology-II

3

PHR 221L

Pharmaceutical Technology Lab-II

1

PHR 222

Medicinal Chemistry-II

3

PHR 223

Pharmaceutical Microbiology-II

3

PHR 223L

Pharmaceutical Microbiology Lab-II

1

PHR 224

Pharmaceutical Analysis-I

3

PHR 224L

Pharmaceutical Analysis-Lab-I

1

PHR 225

Basic Pathology & Toxicology

2

PHR 200

Viva voce

1

Total Credits

22

 


3rd Professional Year (41 credits):

Courses

Titles  

Credits

3rd Year 1st Semester

PHR 310

Pharmaceutical Technology-III

3

PHR 310L

Pharmaceutical Technology Lab-III

1

PHR 311

Pharmaceutical Engineering-I

3

PHR 312

Pharmaceutical Analysis-II

3

PHR 312L

Pharmaceutical Analysis-Lab-II

1

PHR 313

Pharmacology & Clinical Pharmacy-II

3

PHR 313L

Pharmacology Lab-I

1

PHR 314

Bio pharmaceutics & Pharmacokinetics-I

3

PHR 315

Pharmacy Practice-I

3

Total Credits

21

3rd Year 2nd Semester

PHR 314L

Bio pharmaceutics & Pharmacokinetics Lab-I

1

PHR 222L

Medicinal Chemistry Lab-II

1

PHR 320

Medicinal Chemistry-III

3

PHR 321

Pharmacy Practice-II

3

PHR 322

Cosmetology

2

PHR 322L

Cosmetology Lab

1

PHR 323

Pharmaceutical Regulatory Affairs

2

PHR 324

Pharmacology & Clinical Pharmacy-III

3

PHR 325

Pharmaceutical Biotechnology

3

PHR 300

Viva voce

1

Total Credits

20

 


4th Professional Year (31 credits):

Courses

Titles  

Credits

4th Year 1st Semester

PHR 410

Advanced Pharmaceutical Analysis

3

PHR 411

Pharmacology & Clinical Pharmacy-IV

3

PHR 411L

Pharmacology Lab-II

1

PHR 412

Pharmaceutical Engineering-II

3

PHR 413

Bio pharmaceutics & Pharmacokinetics –II

3

PHR 413L

Bio pharmaceutics & Pharmacokinetics-Lab-II

1

PHR 414

GMP & Pharmaceutical Industrial Practices

2

PHR 415

Pharmaceutical Technology-IV

3

Total Credits

19

4th Year 2nd Semester

PHR 420

Pharmaceutical Management

2

PHR 421

Pharmaceutical Marketing

3

PHR 422

Project

5

PHR 423

Internship

1

PHR 400

Final viva voce

1

Total Credits

12

Course Description

1st year 1st semester

PHR 110 - Introduction to Pharmacy                                               

Course Detail:

The course will give an idea on history, evolution, scope and its importance related to pharmaceutical sciences. An introductory study of the pharmacy profession. Ethics and Pharmacy Profession. Scope of pharmacy profession, in different areas, sucha as, community, industry, government, etc. History and evolution; Modern, Ayurvedic, Unani, Homeopathic and other systems of medicines; Information resources for pharmaceutical science. Definition of drugs, Definition and classifications of different types of dosage forms. 

[Pre-requisite ]
[Credit Hours: 2]

Recommended Books:

1. Remington's Pharmaceutical Sciences.

PHR 111 - Communication & Computer Application in Pharmaceutical Sciences

Course Detail:

Provides a general understanding of computer applications and functions of the components of a computer system. Topics include components of computer systems; concepts of software; introduction to operating systems; history of computer languages; programming fundamentals; basics such as constant, variables, data type, operators and expressions, pointer; concepts of database; internet technology and World Wide Web. This course undertaken in a lab setting also provides functional orientation to word processing, spreadsheet, presentation, database and WebPages design. Students also learn some basic skills in searching and evaluating online resources. Advance use of statistical tools (SPSS, Sigma plot). 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Peter Norton's Introduction to Computers. Fifth Edition, McGraw Hil, International Edition.
2. Computer Fundamentals. Dr M. Lutfar Rahman & Dr M. Alamgir Hossain.
3. Computer Fundamentals. P.K Sinha. University of Tokeyo, Japan.
4. The Complete Reference Offic 2000. Stephen L. Nelson. McGraw Hil Publishing Company Limited.

 

PHR 112 - Statistics in Pharmaceutical Sciences

Course Detail:

Statistics and its application. Variables and Attributes. Classification and tabulation of data. Populations and samples. Frequency distributions. Graphical presentation of data. Describing and summarizing data: statistical averages & measures of dispersion. probability andprobability distributions. Hypothesis testing: concepts, types, p-value. Test of significance: parametric tests (t-test, One way ANOVA, multiple comparison tests (Bonferoni, Duncan, Dunnet, Tukey), repeated measure ANOVA; Non-parametric tests: Mann-whiteney, Wilcoxon rank test, Kruskal-Wallis test, multiple comparison tests (Tukey), Friedman's test. Regression (simple linear & nonparametric regression) and correlation (simple & rank correlation), Chi-square & odds ratio. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Basic Statistics and Pharmaceutical Applications. James E. De Muth.
2. Pharmaceutical Statistics. Standards Bolton.
3. Method in Biostatistics. B.K. Mahajan.
4. Sidney Siegel's Nonparapetric Statistics for the behavioral sciences.
5. Biostatistics: A Foundation for analysis in the health sciences. Wayne W. Daniel.

 

PHR 113 - Pharmacognosy

Course Detail:

This is an introduction to the origin of medicines and pharmaceuticals, searching of a novel molecule as a tool for discovery of new drugs or molecular modification of existing drugs from plants, implication of plants and animals? secondary metabolites as pharmaceuticals and medicines and their purification techniques. Introduction and history; Origin of drug discovery; Scope and limitation of pharmacognosy in modern or western medicine systems; Crude drugs: Introduction; Classification; Preparation for the commercial market; Evaluation of drugs; Drug adulteration. Pharmaceutical uses of lipids and its derivatives; Carbohydrates and its derivatives; and vitamin containing animal drugs. Medicinal plants of Bangladesh: Introduction, economic aspects, applications and limitations. Important classes of secondary metabolites and their role in the development of modern medicines and pharmaceuticals. Photochemistry, therapeutic and pharmaceutical uses of plants containing alkaloids, glycosides types of drugs, volatile oils, tannins and resins. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Pharmacognosy. Varro E. Tyler, Lynn R. Brady & James E. Robbers.
2. Pharmacognosy. Trease and Evans.
3. Text book of Pharmacognosy. T.E. Wallis.
4. Practical Pharmacognosy. R. Zafar

 

PHR 113L - Pharmacognosy Lab

Course Detail:

Study of some medicinal plant of Bangladesh. General test for carbohydrates e.g. glucose, fructose, lactose, sucrose, maltose etc. Examinations of starch and related products. Extraction and identification of some anthraquinone derivatives from senna cascarda, sagrada, aloe. Extraction & Identification of Caffeine from tea, coffee. Separation of different substances by thin-layer chromatography (TLC). Study of cardiac glycosides and some cardio-active drugs: Digitalis, squill, strophanthus. Examination of some saponin containing drugs: sarsaparilla, discorea. Study of alkaloids and some alkaloid containing drugs: Belladonna, stramonium, hyoscyamus, cinchona, rauwolfia nux-vomica, ergot, ephedra, colchicum. 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 114 - Organic Pharmacy-I

Course Detail:

The objective of the course is to introduce the physical and chemical behavior of organic molecules, types of reactions, important reactions used to synthesize drugs and pharmaceuticals in the laboratory and their purification. Principles of various types of reactions; Alkane, alkene and alkynes; Aldehyde and ketone; Alcohols, ethers and epoxides; Carboxylic acids; Amines. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Organic Chemistry - Morrison and Boyd.
2. Textbook of Organic Chemistry - Bahl and Bahl.
3. Organic Chemistry, Vo1. I & II-Finar.
4. Organic Chemistry - Feiser and Feiser.
5. An Introduction to Organic Chemistry - Bahl and Bahl.
6. Introduction to organic laboratory techniques- Pavia and Lampman

 

PHR 114L - Organic Pharmacy Lab-I

Course Detail:

Qualitative Analysis of organic salts. 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 115 - Pharmaceutical calculations

Course Detail:

This course is designed to equip studets with different calculations and functions involved in the dispensing and production of pharmaceuticals. Foundamentals of measurements and calculations. Interpretition of presecription or medication order. The metric system; calculation of dose; reducing and enlarging of formula; density, specific gravity, specific volume; percentage and ratio strength; dilution and concentration; isotonic solutions, electrolyte solutions, rate of flow calcultion, other calculations. 

[Pre-requisite ]
[Credit Hours: 2]

Recommended Books:

1. Pharmaceutical Chemistry. L.G. Chatten.
2. Text book of Pharmaceutical Analysis. K. A. Connors.
3. Pharmaceutical Drug Analysis. Ashutosh.
4. Elementary Organic Spectroscopy. Y. R. Sharma.

1st Year 2nd Semester

 

PHR 120 - Inorganic Pharmacy

Course Detail:

An introduction to the inorganic chemicals used in the pharmaceuticals and studying their basic laws and behaviors. Structure of the atom and molecules. The chemistry of co-ordination compounds. Study of medicinal inorganic compounds, such as, Antioxidants; Gastrointestinal agents; Dental preparations; Topical agents, etc. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Inorganic Medical & Pharmaceutical Chemistry. John H. Block.
2. Bentley and Driver's Text book of Pharmaceutical Chemistry.

 

PHR 120L - Inorganic Pharmacy-Lab

Course Detail:

Qualitative analysis of Inorganic compounds., Manufacturing of Inorganic Drugs, such as aluminium hydroxide, ferrous ferrous sulfate. 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 121 - Human Physiology-I

Course Detail:

This course is an introduction to the functions of cells and biological membranes. Transport of molecules through biological membrane. Different types of tissues and organs constituting the human body; role of blood and blood cells, role of cardiovascular system for transport of nutrients and elimination of wastes from the cells; maintaining blood pressure; role of gastrointestinal tract for absorption and metabolism of foods for producing cellular energy; role of kidney on elimination of processes. Cell; Blood; Circulatory system; Alimentary system. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Text book of Medical Physiology. Guyton & Hall.
2. Review of Medical Physiology. William F. Ganong.

 

PHR 122 - Organic Pharmacy -II

Course Detail:

Chemistry of aromatic compounds such as benzene,different aromatic acids,amerius;aldelyde and ketones etc, types of reactions such as nucleophilic and electrophilic reactions,synthesis of different important aromatic drugs and pharmaceuticals;stereochemistry. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. A test book of Organic Chemistry. B.S. Bahl and Arun Bahl.
2. Organic Chemistry. I.L. Finer.
3. Vogel's Text Book of Practical Organic Chemistry.
4. Practical Organic Chemistry. Shrinere et al.
5. Advance Practical Organic Chemistry. N.K. Visnol.
6. Organic Practical Chemistry. Clark.

 

PHR 122L - Organic Pharmacy Lab-II

Course Detail:

Qualitative Analysis of organic salts. 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 123 - Physical Pharmacy-I

Course Detail:

The course is designed to make familiar the physical properties of molecules in different states, the kinetic behavior of drugs, equilibrium nature of molecules in liquid, solid and gaseous phases, ionization character of drugs in solution and determination of stability or self-life of drugs by considering physical factors. States of matter: Gaseous state, liquid state, solid state, polymorphism. Changes in the state of matter: Latent heat, vapor pressure, boiling point, meting point and freezing point, sublimation, eutectic mixtures, aerosols. Solutions: Ideal and real solutions, Henry?s law, Nernst?s distribution law, solubility. Colligative properties of dilute solutions. Ionic equilibria: pH of solutions, acids and bases. Buffers and buffering agents: Buffer action, buffer equation, buffer capacity, biological and pharmaceutical buffers, buffered isotonic solutions. Chemical kinetics and drug stability: Rate and molecularity of reactions, Integrated rate equations; stability testing; accelerated stability studies, prediction of self-life, limitations of accelerated stability studies. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Essentials of Physical Pharmacy. B.S. Bahl, G.D. Tuli, Arun Bahl.
2. Physical Pharmacy. S.P. Aqarwal, Rajesh Khanna.
3. Physical Pharmacy. Alfred Martin

 

PHR 124 - Pharmaceutical Microbiology-I

Course Detail:

It deals with the basic knowledge of different groups of microorganisms and also a detailed study of morphology, nutrition, growth, cultivation and preservation of bacteria. Microscopy: Bright field, dark field, fluorescence, phase contrast, electron microscopy. Properties of selected bacterial species. Study of yeast, molds and viruses. Principle of microbial pathogenesis and epidemiology. Mircrobiological spoilage and preservation of pharmaceutical products. Contamination of non sterile pharmaceuticals and preservation of pharmaceutical products.Chemical disinfectants, antiseptics and preservatives. Contamination of non-sterile pharmaceuticals in hospital and community environment. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Pharmaceutical Microbiology, Hugo & Russel.
2. Microbiology. Michael Pelczar.

 

PHR 124L - Pharmaceutical Microbiology-Lab-I

Course Detail:

Study of compound microscope. Preparation of pure bacterial cultures. Preparation of pure culture and its identification. Bacterial counts. Study of Gram-staining. Culture sensitivity test by disk-diffusion method. Minimum inhibitory concentration of antibiotic 

[Pre-requisite ]
[Credit Hours: 1]

 

2nd Year 1st Semester

PHR 210 - Physical Pharmacy-II

Course Detail:

The objective of the course is to introduce students? to dynamic of drugs or molecules and behavior of molecules in dispersed systems. The dissolving characteristic of drugs or small molecules, drug delivery systems, and surface-active properties of molecules and electrical behavior of molecules will be known. Chemical thermodynamics: Introduction, scope and limitations; Thermodynamic terms and basic concepts; First law of thermodynamics; Colloidal dispersions: Interaction and stability of colloids, pharmaceutical applications of colloids. Types of colloidal dispersions, preparations, properties and purification of colloids: Diffusion and dissolution: Fick?s law of diffusion, steady state diffusion, diffusion study, diffusion principles in biological systems. Dissolution: Drug release, drug release from modern drug delivery systems Phase Rule; Surface and interfacial phenomena: Surface and interfacial tension, adsorption at liquid surfaces, classification of surfactants, HLB system, critical micelle concentration, application of surface active agents Electrochemistry: Introduction and concepts of particle size determination, Different means of expressing particle size, Methods of particle size determination. Pre-formulation studies; Physical and chemical incompatibilities. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Essentials of Physical Pharmacy. B.S. Bahl, G.D. Tuli, Arun Bahl.
2. Physical Pharmacy. S.P. Aqarwal, Rajesh Khanna.
3. Physical Pharmacy. Alfred Martin

 

PHR 210L - Physical Pharmacy-Lab

Course Detail:

Preparation of solutions of different pH. Preparation of buffer. Standardization of acids & bases. Determination of the velocity constant of acid catalyzed hydrolysis of methy1 acetate at a known temperature. Determination of adsorption isotherm of oxalic (or acetic) acid from aqueous solution by charcoal and calculation of the constant in Freundlich?s equation. Determination of energy of flow of a liquid through a capillary by measuring viscosity as a function of temperature. Determination of the equilibrium constant of the reaction KI +I2 = KI3 at a known temperature. Determination of the velocity constant of the hydrolysis of ethyl acetate in the basic medium. Determination of viscosity of pure liquids such as glycerin, alcohol and nitrobenzene using Ostwald viscometer. Study of variation of viscosity of a liquid with temperature using Ostwald or Engler?s viscometer. Determination of solubility of a sparingly soluble salt in water by conductance measurement. Determination of velocity constant for the hydrolysis of an ester in the basic medium by conductance measurements. 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 211 - Human Physiology-II

Course Detail:

This course deals with the functions of neuron for generation and transmission of different kind of impulses or responses to the human brain, regulation of different types of cellular activities; organs and enzymes involved on bio-transformation of foods and other foreign particles; role of endocrine glands for the generation of hormones which are playing role for growth and maintenance of the human body. Function of lung for air transport. Nervous system; Excretory system; Respiratory system. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Text book of Medical Physiology. Guyton & Hall.
2. Review of Medical Physiology. William F. Ganong.

 

PHR 211L - Human Physiology Lab

Course Detail:

 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 212 - Pharmaceutical Technology-I

Course Detail:

In this course the students will start learning of basic principles and technological matters related to dosage form manufacturing. The course begins with the pharmaceutical excipients used in manufacturing of dosage forms. Physico-chemical properties of drug molecules. Factors affecting solubility and the manufacture and quality control of liquid dosage forms. Theoretical aspects of disperse systems and the formulation and manufacture of emulsion and suspension, their stability considerations and quality control systems. Formulation, manufacture and quality control of semisolid dosage forms such as ointments, creams and gels. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Industrial Pharmacy, Lachman. 3rd Ed.
2. Modern Pharmaceutics: Banker, 4th Edition.
3. Pharmaceutics: The dosage form design: Aulton.
4. Bentley' Text book of Pharmaceutics, edited by E.A. Rawlins. 8th Edition.

 

PHR 212L - Pharmaceutical Technology Lab-I

Course Detail:

Physical checking of emulsions suspensions, syrups, ointments, suppositories? etc. Formulation of emulsions, suspensions, syrups, ointments, suppositories etc. Preparations, problems encountered during preparation, physical evaluation of the different dosage forms: i) Tablets including coated tablets, ii) Capsules, iii) Suppositories, iv) Pharmaceutical Aerosols. 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 213 - Biochemistry & Cell Biology

Course Detail:

 

[Pre-requisite ]
[Credit Hours: 3]

 

PHR 214 - Pharmacology & Clinical Pharmacy-I

Course Detail:

Introduction to pharmacology, history, scope, limitation and pharmacological terminology. Routes of drug administration and its fate. Autocoids: Histamin, Bradykinens and their antagonists. Lipid derived autocoids, analgesics, antipyretic and anti-inflammatory agents. Drug used in the treatment of asthma. The vitamins: water soluble and fat soluble vitamins. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. The Pharmacological Basis of Therapeutics (10th Edition). Goodman & Gilman.
2. Medical Pharmacology (5th Edition). HP Rang, MM Dale, JM Ritter.
3. Basic and Clinical Pharmacology (8th Edition). Bertram G Katzung

 

PHR 215 - Medicinal Chemistry-I

Course Detail:

This course examines discovery and synthesis of drugs from nature and in the laboratory, how a small organic molecule interact with cellular components of the human and other animals, how chemical nature of the small molecules influence or exhibit biological activities, structural modifications leads potential activity or minimize toxicity of the parent molecules and design and development of new drugs. Stereochemistry; Molecular modifications of H-1 and H-2 blockers; Molecular modifications of diuretics; Molecular modifications of analgesic, antipyretics and anti-inflammatory drugs; Molecular modifications of anti-aging drugs. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Essentials of Medicinal Chemistry. Andrejus Korolkovas.
2. Heteerocyclic Chemistry. T.L. Gilchrist. Pitman Publishing Ltd.
3. Burger's Medicinal Chemistry.
4. Foy's Medicinal Chemistry.

2nd Year 2nd Semester

PHR 215L - Medicinal Chemisty Lab-I

Course Detail:

Synthesis of organic compounds of medicinal importance, exercises on stereo-chemistry & drug receptor interactions, studies of drug design, extraction of metabolic enzymes from liver and their effects. 

[Pre-requisite ]
[Credit Hours: 1]

.

PHR 220 - Human Physiology-III

Course Detail:

The course id designed for to make the student familiar with the physiological role of Reproductive systems of both sexes; its function for reproduction; maintenance of sex characteristics; role of sex hormones; factors influencing male & female reproductively and maintenance of fertility; pregnancy & lactation; Enzymes involved in primary metabolism of carbohydrate, fat and protein & glands involved secretion of enzymes for metabolism in the body; route of absorption of primary metabolized in the body; factors influencing absorption and metabolism etc; role of endocrine systems for biosynthesis and release of hormones; vital physiological roles of hormones for normal functions and factors influencing hormone production; pathology of hormonal abnormality. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Text book of Medical Physiology. Guyton & Hall.
2. Review of Medical Physiology. William F. Ganong.

 

PHR 221 - Pharmaceutical Technology-II

Course Detail:

This course includes the study of solid dosage forms. The properties of powders and granules. The formulation, manufacture and quality control of tablets. Tableting problems and its remedy. The physics of tablet compression. The capsule dosage forms. The study of gelatin and gelatin shell. Capsule manufacturing machines, formulations and quality control. Tablet coating technology, sugar coating, film coating and modified release coating, coating formulations, coating polymers, coating machines and coating problems. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Industrial Pharmacy, Lachman. 3rd Ed.
2. Modern Pharmaceutics: Banker, 4th Edition.
3. Pharmaceutics: The dosage form design: Aulton.
4. Bentley' Text book of Pharmaceutics, edited by E.A. Rawlins. 8th Edition.

 

PHR 221L - Pharmaceutical Technology Lab-II

Course Detail:

Physical checking of emulsions suspensions, syrups, ointments, suppositories? etc. Formulation of emulsions, suspensions, syrups, ointments, suppositories etc. Preparations, problems encountered during preparation, physical evaluation of the different dosage forms: i) Tablets including coated tablets, ii) Capsules, iii) uppositories, iv) Pharmaceutical Aerosols 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 222 - Medicinal Chemisty-II

Course Detail:

This course examines how drugs act on cells at pathological state or diseased state, how drugs are developed by structural modifications, influence of structure on pharmacological activities of different types of diseases. Basic concepts on mechanism of action of drugs; Molecular modifications of antidepressant drugs; Molecular modifications of hypnotics, sedatives and tranquilizers; Molecular modifications of cardiovascular drugs; Molecular modifications of oral contraceptives and sex steroids. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Essentials of Medicinal Chemistry. Andrejus Korolkovas.
2. Heteerocyclic Chemistry. T.L. Gilchrist. Pitman Publishing Ltd.
3. Burger's Medicinal Chemistry.
4. Foy's Medicinal Chemistry.

 

PHR 223 - Pharmaceutical Microbiology-II

Course Detail:

The course is designed to equip the students about the applied areas of microbiology in industrial pharmacy, its role in production and quality control of pharmaceutical products of industrial importance. The course also includes the detailed study of sterilization process and its applications in pharmacy. Principle and practice of sterilization. Sterilization by dry heat and moist heat; Sterilization by gas, radiation sterilization and sterilization by membrane filter. Sterilization control and sterility assurance. Fundamentals of immunology. Manufacture and quality control of immunological products.  

[Pre-requisite ]
[Credit Hours: 3]

 

PHR 223 - Pharmaceutical Microbiology-II

Course Detail:

The course is designed to equip the students about the applied areas of microbiology in industrial pharmacy, its role in production and quality control of pharmaceutical products of industrial importance. The course also includes the detailed study of sterilization process and its applications in pharmacy. Principle and practice of sterilization. Sterilization by dry heat and moist heat; Sterilization by gas, radiation sterilization and sterilization by membrane filter. Sterilization control and sterility assurance. Fundamentals of immunology. Manufacture and quality control of immunological products.  

[Pre-requisite ]
[Credit Hours: 3]

 

PHR 223L - Pharmaceutical Microbiology Lab-II

Course Detail:

Study of compound microscope. Preparation of pure bacterial cultures. Preparation of pure culture and its identification. Bacterial counts. Study of Gram-staining. Culture sensitivity test by disk-diffusion method. Minimum inhibitory concentration of antibiotic 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 224 - Pharmaceutical Analysis-I

Course Detail:

Introduce with different chemical and physical techniques used for the identification and estimation or standardization of drugs by using different chemical methods of analysis in the pharmaceutical industry. The art and science of pharmaceutical analysis; Introduction; Techniques; Aqueous acid-base titrations; Oxidation-reduction titrations; Complexometric titrations; Non-aqueous titrations; Aquametry; Polarimetry. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Pharmaceutical Chemistry. L.G. Chatten.
2. Text book of Pharmaceutical Analysis. K. A. Connors.
3. Pharmaceutical Drug Analysis. Ashutosh.
4. Elementary Organic Spectroscopy. Y. R. Sharma.

 

PHR 224L - Pharmaceutical Analysis-Lab-I

Course Detail:

Assay of acetyl salicylic acid in aspirin tablets, non-aqueous assay of phenobarbitone tablets, assay of antazoline hydrochloride in antihistamine tablets, non-aqueous titration of PAS tablets, determination of potency of penicillin tablets, determination of potency of vitamin tablets, determination of calcium gluconate tablets and injections by EDTA titration, determination of saponification value, iodine value and acid value of fixed oils, assay of sulfa-drugs by nitrate titration, microbiological assay of vitamins and antibiotics. 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 225 - Basic Pathology & Toxicology

Course Detail:

This course is designed to give pharmacy students and idea of different patho-physiologic conditions of disease occurrence and progression and the causes of disease manifestations. Diseases: Manifestation and patho-physiology. Cellular injury and death. Adaptations in cellular growth and differentiation, intracellular accumulations and cell ageing. Acute and chronic inflammation. Tissue repair: cellular growth, fibrosis and wound healing. Homodynamic disorders, thrombosis and shock. Genetic disorders. Principle of toxicology: Spectrum of undesired effects, toxicity test in animals, incidence of acute poisoning and its managements. Heavy metal toxicology and antagonists. Non-heavy metal environmental toxicants. Laboratory data and other biochemical parameters of human body. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Robins Pathologic basis of disease: Pocket companion.
2. Pathology illustrated. A.D.T. Govan.

 

3rd Year 1st Semester

PHR 310 - Pharmaceutical Technology-III

Course Detail:

Drug delivery to the lungs, its mechanism. Theory of compressed delivery system, aerosol. Aerosol manufacturing and quality control systems. Metered dose inhalers (MDI) and dry powder inhalers (DPI). Concepts of Controlled drug delivery systems and its applications. Manufacture of different oral sustained release systems. Evaluation techniques of sustained release drug delivery systems. Rectal drug delivery system, such as suppository. Its formulation, manufacturing and quality control systems. Pharmaceutical packaging science. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Industrial Pharmacy, Lachman, 3rd Edition.
2. Sterile dosage forms, S.J. Turco.
3. Parenteral dosage forms. Vol 1 & 2. Lachman.

PHR 310L - Pharmaceutical Technology Lab-III

Course Detail:

Preparation, Problems encountered during preparation, physical evaluation of different dosage forms: Micro-capsules, parenteral products, opthalmic preparations, Sustained release products. 

[Pre-requisite ]
[Credit Hours: 1]

PHR 311 - Pharmaceutical Engineering-I

Course Detail:

This course includes the essential unit operations used in manufacturing of various pharmaceutical dosage forms. The fundamentals of unit operations, such as fluid flow, heat transfer and mass transfer. This course also covers various pharmaceutical process. Drying, theory of drying, drying mechanism, dryers used in pharmaceutical process. Filtration, theory of filtration, different types of filters used in pharmaceutical manufacturing. Mixing, mixing process, different types of solid and liquid mixtures. Size reduction and classification. Evaporation and distillation. Crystallization. Construction materials for pharmaceutical machines, equipments and piping system.  

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Industrial Pharmacy. Lachman, 3rd Edition.
2. Pharmaceutical process engineering.
3. Physical Pharmaceutics, Shotton & Ridgway.

PHR 312 - Pharmaceutical Analysis-II

Course Detail:

Introduce with various physical techniques used for the identification, characterization, molecularweight determination and estimation or standardization of drugs or pharmaceuticals in pharmaceutical industry. Chromatographic methods of analysis; Spectroscopy: Visible, UV, IR. 

[Pre-requisite ]
[Credit Hours: 3]

PHR 312L - Pharmaceutical Analysis-Lab-II

Course Detail:

Assay of acetyl salicylic acid in aspirin tablets, non-aqueous assay of phenobarbitone tablets, assay of antazoline hydrochloride in antihistamine tablets, non-aqueous titration of PAS tablets, determination of potency of penicillin tablets, determination of potency of vitamin tablets, determination of calcium gluconate tablets and injections by EDTA titration, determination of saponification value, iodine value and acid value of fixed oils, assay of sulfa-drugs by nitrate titration, microbiological assay of vitamins and antibiotics. 

[Pre-requisite ]
[Credit Hours: 1]

PHR 313 - Pharmacology & Clinical Pharmacy-II

Course Detail:

Drugs used in infectious disease. Antimicrobial, antifungal and anti viral agents. Sulfonamides, Quinolone derivatives; Penicillins and cephalosporins, amino-glycosides, miscellaneous antibacterial agents. Topical and systemic antifungal agents. Anti viral agents, such as, anti-herpes, anti-influenza and others. Chemotherapy of neoplastic disease: Different anti-neoplastic agents. Drugs used in immunomodulation: Immunomodulators, immuno-suppressive agents, tolerogens, immuno-stimulants. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. The Pharmacological Basis of Therapeutics (10th Edition). Goodman & Gilman.
2. Medical Pharmacology (5th Edition). HP Rang, MM Dale, JM Ritter.
3. Basic and Clinical Pharmacology (8th Edition). Bertram G Katzung

PHR 313L - Pharmacology Lab-I

Course Detail:

Maintenance and handling of experimental animals, routes for drug administration. Effect of CNS stimulants and depressants on rats. Effect of drugs on gastrointestinal (GI) motility and GI absorption of rats.  

[Pre-requisite ]
[Credit Hours: 1]

PHR 314 - Biopharmaceutics & Pharmacokinetics-I

Course Detail:

This course includes the techniques used to assess the availability of the pharmaceutical product inside the body so as to ensure its proper therapeutic efficacy. Importance; Gastro-intestinal absorption of drugs; Biological, physicochemical and dosage form considerations; Disintegration and dissolution of drugs; Distribution of drugs with important pharmacokinetic parameters; Interpretation of drug-plasma level curve; Drug-protein interaction; Theoretical aspects of drug clearance; Elimination, excretion and biotransformation; Renal pathway of elimination; Hepatic elimination; Biliary excretion; Purpose of bioavailability; Methods of assaying bioavailability; Criteria for bioequivalence studies; Drug product selection on the basis of bioavailability testing. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Biopharmaceutics & Clinical Pharmacokinetics. M. Gibaldi.
2. Biopharmaceutics & Clinical Pharmacokinetics. Notari.
3. Pharmacokinetics. M. Gibaldi & D. Perrier.

PHR 315 - Pharmacy Practice-I

Course Detail:

This course deals with the various aspects of pharmaceutical practice related to patients, community and hospitals. The prescription and abbreviations used in prescription, Extemporaneous prescription compounding. Labelling of dispensed medications. Techniques in radiopharmacy and clinical applications of radiopharmaceuticals. Wound management products and surgical dressings. 

[Pre-requisite ]
[Credit Hours: 3]

 

3rd Year 2nd Semester

PHR 314L - Biopharmaceutics & Pharmacokinetics-Lab I

Course Detail:

In vivo study of bio-availability of drug: Determination of concentration of aspirin in urine after oral administration. Determination of paracetamol in blood after oral administration. In vitro study of bio-availability of drug: Disintegration and dissolution tests of solid dosage forms. Determination of viscosity of a prepared emulsion 

[Pre-requisite ]
[Credit Hours: 1]

PHR 222L - Medicinal Chemistry Lab-II

Course Detail:

Synthesis of organic compounds of medicinal importance. Exercises on stereo-chemistry & drug receptor interactions. Studies of drug design. Extraction of metabolic enzymes from liver and their effects. 

[Pre-requisite ]
[Credit Hours: 1]

PHR 320 - Medicinal Chemistry-III

Course Detail:

This course deals with discovery processes of several classes of drugs, tools used for drugs discovery, conventional drug discovery versus modern tools and their advantages and limitations. Basic concept on drug design and drug discovery; Molecular modifications of antineoplastic drugs; Molecular modifications of antibiotics such as b-lactams, cephalosporins etc.; Molecular modifications of anti-tubercular drugs; Molecular modifications of anti-thyroid drugs. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Essentials of Medicinal Chemistry. Andrejus Korolkovas. 2. Heteerocyclic Chemistry. T.L. Gilchrist. Pitman Publishing Ltd. 3. Burger's Medicinal Chemistry 4. Foy's Medicinal Chemistry.

PHR 321 - Pharmacy Practice-II

Course Detail:

This course has been designed to understand the patient-pharmacist relationships at various level. Ambulatory patient care, Institutional patient care, Long-term care facility, The patient: Behavioral determinants. Patient communications. Patient compliance. Integrated health care delivery system. Home health patient care. Role of pharmacist in the hospital and community. Hospital pharmacy. 

[Pre-requisite ]
[Credit Hours: 3]

PHR 322 - Cosmetology

Course Detail:

This course provides an in-depth understanding about the technology and advancements on various cosmetics preparations. Concepts of designing, formulation, manufacturing, and quality control of Cold cream, Vanishing cream, Transparent shampoo, Egg shampoo, Body lotion, Shaving cream, After shave lotion, Tooth paste, Tooth powder, Mouthwash etc. 

[Pre-requisite ]
[Credit Hours: 3]

PHR 322L - Cosmetology Lab

Course Detail:

Methods of preparation of talcum powder, tooth powder, tooth paste, vanishing and cold cream, shapoo, lotion, after shave, mouth wash, lipstick, lip gel, hair oil. 

[Pre-requisite ]
[Credit Hours: 1]

PHR 323 - Pharmaceutical Regulatory Affairs

Course Detail:

This course focuses on the concepts, working techniques and tools needed to examine and register pharmaceuticals for human use at home and abroad. Drug Act 1940; Drug (Control) Ordinance 1982; Other rules and regulations. Accepted standards of harmonization and technical requirements for the registration of pharmaceuticals for human use; Approval process, format and registration of pharmaceuticals in Bangladesh. This course reviews the recent global developments and trends in all the necessary steps of manufacturing quality pharmaceuticals. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Remingto

PHR 324 - Pharmacology & Clinical Pharmacy-III

Course Detail:

Drugs affecting gastro intestinal functions: Drugs used in gastric acidity and peptic ulcer. Prokinetics, anti-emetics, agents used in IBS. Agents used in constipation and diarrhea. Agents used in biliary and pancreatic disease. Drugs affecting renal and cardio vascular functions: Diuretics, vasopressin and others, renin and angiotensisns, drug used for myocardial ischemia, hypertension, heart failure, anti-arrhythmic drugs and lipid lowering drugs. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. The Pharmacological Basis of Therapeutics (10th Edition). Goodman & Gilman.
2. Medical Pharmacology (5th Edition). HP Rang, MM Dale, JM Ritter.
3. Basic and Clinical Pharmacology (8th Edition). Bertram G Katzung.
4. Clinical Pharmacy and therapeutics. Roger Walker.

PHR 325 - Pharmaceutical Biotechnology

Course Detail:

 4th Year 1st Semester 

PHR 410 - Advanced Pharmaceutical Analysis

Course Detail:

This course is designed for the student to make them familiar with identification, standardization and characterization of organic molecules used in pharmaceutical preparation; studies of degradation pattern and stability of drugs; research skill development in the areas of natural product chemistry, drug design and synthesis and drug metabolite studies- 1H-nmr; 13C-nmr; EIMS; GC-MS; Elemental analysis and hplc methods. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Methods of spectroscopy ? Pavia.
2. Spectroscopy ? William Kemp
3. Spectroscopic Methods ? Sharma
4. Textbook of Pharmaceutical Analysis ? Connor.

PHR 411 - Pharmacology & Clinical Pharmacy-IV

Course Detail:

Drugs affecting on central nervous system: Neurotransmission and central nervous system, sedative and hypnotics, drugs for depression and anxiety, anti-psychotic drugs, drugs for epilepsy, opioid analgesics, general and local anesthetics. Hormone and Hormone antagonist: Putitory hormones, thyroid and antithyroid drugs, Insulin and other oral hypoglycemic agents, estrogens and progestins, androgens, agents affecting calcification. Ocular pharmacology. Dermatological pharmacology. 

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. The Pharmacological Basis of Therapeutics (10th Edition). Goodman & Gilman.
2. Medical Pharmacology (5th Edition). HP Rang, MM Dale, JM Ritter.

3. Basic and Clinical Pharmacology (8th Edition). Bertram G Katzung.

4. Principle of Toxicology. Craset & Dohl.

 

PHR 411L - Pharmacology Lab-II

Course Detail:

In vitro test for the evaluation of drugs acting on the cardiovascular system. Evaluation of anti-inflammatory drugs in caraginine-induced oedema of rats. Analysis and interpretation of experimental data 

[Pre-requisite ]
[Credit Hours: 1]

 

PHR 412 - Pharmaceutical Engineering-II

Course Detail:

This course deals with the various aspects of pharmaceutical industry design and construction. Clean room technology: Definition and classifications, Turbulently ventilated clean rooms, Construction materials and surface finish, High efficiency air filter, Clean room testing and monitoring, Clean room discipline and gowning practice. Cleaning and disinfection of clean rooms. Other issued of pharmaceutical engineering, such as, humidification and dehumidification, HVAC systems, Pharmaceutical water engineering. 

[Pre-requisite ]
[Credit Hours: 3]

PHR 413 - Biopharmaceutics & Pharmacokinetics ?II

Course Detail:

This course includes the techniques used to assess the availability of the pharmaceutical product by compartmental analysis such as single or one compartment model; multiple compartment model; pharmacokinetic of drug absorption; multiple dosage regimen etc. 

[Pre-requisite ]
[Credit Hours: 3]

 

Recommended Books:

1. Biopharmaceutics & Clinical pharmacokinetics-M. Gibaldi.
2. Biopharmaceutics & Clinical pharmacokinetics-Notari.
3. Biopharmaceutics & relevant pharmacokinetics- T.G. Wagner.
4. Biopharmaceutics & Drug interactions-Cadwallader.
5. Pharmacokinetics-M. Gibaldi & D. Perrier

 PHR 413L - Biopharmaceutics & Pharmacokinetics-Lab-II

Course Detail:

In vivo study of bio-availability of drug: Determination of concentration of aspirin in urine after oral administration. Determination of paracetamol in blood after oral administration. In vitro study of bio-availability of drug: Disintegration and dissolution tests of solid dosage forms. Determination of viscosity of a prepared emulsion. 

[Pre-requisite ]
[Credit Hours: 1]

PHR 414 - GMP & Pharmaceutical Industrial Practices

Course Detail:

This course reviews the recent global developments and trends in all the necessary steps of manufacturing quality pharmaceuticals.General provisions, Organization and personnel, Buildings and facilities, Equipment, Control of components and drug product containers and closures, Production and process control, Packaging and labeling control, Holding and distribution, Laboratory controls, Records and reports, Returned and salvaged drug products.General provisions, Organization and personnel, Buildings and facilities, Equipment, Control of components and drug product containers and closures, Production and process control, Packaging and labeling control, Holding and distribution, Laboratory controls, Records and reports, Returned and salvaged drug products 

[Pre-requisite ]
[Credit Hours: 2]

 

Recommended Books:

1. Remington's Pharmaceutical Sciences.

PHR 415 - Pharmaceutical Technology-IV

Course Detail:

Detail study of sterile pharmaceuticals. Formulation, packaging and Manufacturing of small volume parenterals. Different process of manufacturing of small volume parenterals, ampoule filling and dry vial filling mechanisms of small volume parenterals. Large volume parenterals, fundamentals of fluid and electrolyte therapy, large volume parenterals manufacturing, the Blow ?fill-seal technology. Parenteral admixture and incompatibility, Blood components and plasma expenders. Radiopharmaceuticals. Ophthalmic preparations. 

[Pre-requisite ]
[Credit Hours: 3]

 

4th Year 2nd Semester 

 

PHR 420 - Pharmaceutical Management

Course Detail:

This course introduces the students to the basic concepts, styles and tools of pharmaceutical management. Importance; Styles; Improving decision making; Qualities of a manager. Social and legal organizations; Sole proprietorship; General partnership; Public limited company; Private limited company. Personnel management; Principles; Methods; Motivation; Staff requirements theory. Inventory control; Methods; Intuitive; Systematic wantbook; Perpetual inventory; Stock record card; Selection of optimum methods. Purchasing; Effective buying policies; Selecting the sources of supply; Determining terms of purchase; Stocking of goods.  

[Pre-requisite ]
[Credit Hours: 2]

 

Recommended Books:

1. Management: A global perspective by Weirich, Heinz & Koontz.
2. Principles and Methods of Pharmacy Management by H.A. Smith
3. Marketing Management by Philip Kotler & Garry Armstrong
4. Basic Principles of Marketing by Jeorge R. Terry
5. Macroeconomic Analysis by Shappiro
6. Microeconomics - Schaum?s outline series
7. Macroeconomics - Schaum?s outline series
8. Microeconomic Theory ? K.K. Dewett
9. Economics ? Samuelson

PHR 421 - Pharmaceutical Marketing

Course Detail:

This course discusses various aspects of essential marketing operations in a pharmaceutical company. Pricing of drugs: Competitive strategies of pricing; Pricing methods. Market Promotion: Approaches; Developing a promotional plan; Executing the program; Steps in implementation; Advertising of drugs; Direct mail; Personal selling; Miscellaneous promotion; Limiting factors; Evaluation. Advertising: Classification; Primary and selective demand; Strategy; Appraising the opportunity; Media planning; Measuring effectiveness. Market demand and forecasting: Understanding market demand; Anatomy of a market; Patterns; Forecasting and planning; Using multiple forecasting methods.  

[Pre-requisite ]
[Credit Hours: 3]

Recommended Books:

1. Management: A global perspective by Weirich, Heinz & Koontz
2. Principles and Methods of Pharmacy Management by H.A. Smith
3. Marketing Management by Philip Kotler & Garry Armstrong
4. Basic Principles of Marketing by Jeorge R. Terry
5. Macroeconomic Analysis by Shappiro
6. Microeconomics - Schaum?s outline series
7. Macroeconomics - Schaum?s outline series
8. Microeconomic Theory ? K.K. Dewett
9. Economics ? Samuelson

PHR 422 - Project

Course Detail:

This is a research course. This course is designed to equip the undergraduate students with the basic methodology of continuing research on various disciplines of pharmaceutical sciences. The students will have to submit a dissertation for partial fulfillment of Bachelor of Pharmacy degree. 

[Pre-requisite ]
[Credit Hours: 5]

PHR 423 - Internship

Course Detail:

This internship training, report submission and evaluation is required for all the students before conferring the Bachelor of Pharmacy degree. This internship training is mandatory for all the students after they have completed at least 140 credits. The internship will be arranged in pharmaceutical industries located in Bangladesh. 

[Pre-requisite ]
[Credit Hours: 1]

Course Outline

Course Outline info will be available soon

Undergrad