Dr. Murad Hossain

Full Time Faculty
Assistant Professor

MPharm. & Ph.D., Niigata University of Pharmacy and Applied Life Sciences, Japan
BPharm., Faculty of Pharmacy, University of Dhaka, Bangladesh.

Phone: +880-2-55668200 Ext: 1961
Email: murad.hossain@northsouth.edu
Office: SAC1067

Curriculum Vitae

Dr. Murad  Hossain, PhD, has recently joined the Department of Pharmacy NSU as an Assistant Professor. Before joining, he was an Assistant Professor in the Department of Pharmacy at University of Asia Pacific (UAP) Bangladesh.

Dr. Murad completed his Bachelor of Pharmacy from the Faculty of Pharmacy at Dhaka University in Bangladesh. He earned both his Master’s and Ph.D. in Pharmacology from Niigata University of Pharmacy and Applied Life Sciences (NUPALS), Japan.  After completion of Ph.D. in 2010, he worked as postdoctoral research at NUAPALS, the University of North Dakota (UND), USA and University of Illinois at Chicago (UIC), USA. 

List of Publications:

1. Ulla A, Mohamed MK, Sikder B, Rahman AT, Sumi FA, Hossain M, Reza HM, Rahman GMS, Alam MA. Coenzyme Q10 prevents oxidative stress and fibrosis in isoprenaline induced cardiac remodeling in aged rats. BMC Pharmacol Toxicol, 18(1):29 (2017)

2. Alam MA, Subhan N, Hossain H, Hossain M, Reza HM, Rahman MM, Ullah MO. Hydroxycinnamic acid derivatives: a potential class of natural compounds for the management of lipid metabolism and obesity. Nutr Metab (Lond), 11, 13:27 (2016)

3. Safratwoich BD, Hossain M, Bianchi L, Carvelli L. Amphetamine Potentiates the Effects of β-Phenylethylamine through Activation of an Amine-Gated Chloride Channel. Journal of Neuroscience, 34(13):4686-91(2014)

4. Hossain M, Wickramasekara RN, Carvelli L. β-Phenylethylamine requires the dopamine transporter to increase extracellular dopamine in Caenorhabditiselegans dopaminergic neurons. Neurochemistry International Journal, 34(13):4686-91 (2014)

5. Hossain M, Muntasir HA, Ishiguro M, Bhuiyan MA, Rashid M, Sugihara T, Nakamura T, Nagatomo T. Mechanism of inverse agonist activity of sarpogrelateat the constitutively active mutant of human 5-HT2A receptor revealed by molecular modeling. Biological and Pharmaceutical Bulletin, 35(9):1553-9 (2012)

6. Hao J, Chen B, Yao Y, Hossain M, Nagatomo T, Yao H, Kong L, Sun H. Practical access to four stereoisomers of naftidrofuryl and their binding affinity towards 5-hydroxytryptamine 2A receptor. Bioorganic & Medicinal Chemistry Letters, 22(10):3441-4(2012)

7. Bhuiyan MA, Hossain M, Ishiguro M, Nakamura T, Nagatomo T. Engineered Mutation of Some Important Amino Acid in Angiotensin II Type 1(AT1) Receptor Causes Increase in Binding Affinity of AT1 Receptor Antagonists. Journal of Pharmacological Science, 113, 57-65 (2010)

8. Bhuiyan MA, Hossain M, Nakamura T, Ozaki M, and Nagatomo T. Internalization of Constitutively Active N11G Mutant of AT1 Receptor Induced by Agiotensin II Receptor Antagonist Candesartan, Losartan, and Telmisartan: Comparison with Valsartan. Journal of Pharmacological Sciences, 112, 459-462 (2010)

9. Hossain M, Bhuiyan MA and Nagatomo T. Pharmacological and Molecular Studies for the regulation of β1-Adrenergic Receptor that Reveals Activation and Inactivation, Pharmacomatrics, 78(1/2) 1-9 (2010)

10. Bhuiyan MA, Hossain M, Masanobu W and Nagatomo T. Selectivity of Valsartan to the Human Angiotensin II Type One Receptor as Assessed by Binding Affinity, Functional Activity and Molecular Modeling. Pharmacomatrics, 78 (1/2) 11-20 (2010)

11. Hossain M, Bhuiyan MA, Nakamura T, Ozaki M, and Nagatomo T. Mutagenesis of Important Amino Acid Reveals Unconventional Homologous Internalization of β1-Adrenergic Receptor. Life Science, 85, 339-344 (2009)

12. Bhuiyan MA, Hossain M, Miura S-I, Nakamura T, Ozaki M, and Nagatomo T. Constitutively Active mutant N111G of AT1 receptor induces homologous internalization through mediation of AT1 receptor antagonist. Journal of Pharmacological Sciences, 111(3):227-34 (2009)

13. Aly SAR, Hossain M, Bhuiyan MA, Nakamura T and Nagatomo T. Assessment of binding affinity to 5-HT2A receptor and inverse agonist activity of Naftidrofuryl: comparison with those of Sarpogrelate. Journal of Pharmacological Sciences, 110, 445-450 (2009)

14. Bhuiyan MA, Ishiguro M, Hossain M, Nakamura T, Ozaki M, Miura S-I, Nagatomo T. Binding sites of valsartan, candesartan and losartan with angiotensin II receptor 1 subtype by molecular modeling. Life Science, 85(3-4), 136-40 (2009)

15. Hossain M, Ahmed M, Bhuiyan MA, Ishiguro M, Tanaka T, Muramatsu I and Nagatomo T. Mutation of important amino acid residue of residue of asp104lys in human β1-adrenergic receptor triggers functional and constitutive inactivation”, Biological and Pharmaceutical Bulletin, 33(8), 1517-1522 (2008)

16. Ahmed M, Hossain M, Bhuiyan MA, Ishiguro M, Tanaka T, Muramatsu I and Nagatomo T. Mutational analysis of the α1a-adrenergic receptor binding pocket of antagonists by radioligand binding assay. Biological and Pharmaceutical Bulletin. 31(4) , 598-601(2008)

17. NagaokaY, AhmedM, HossainM, Bhuiyan MA, IshiguroM, NakamuraT, Watanabe M and NagatomoT. Amino acids of the human α1d-adrenergic receptor involved in antagonist binding. Journal of Pharmacological Sciences.106 (1) (2008)

18. Takahashi K, Hossain M, Ahmed M, Bhuiyan MA, Ohnuki T, Nagatomo T. Asp125 and Thr130 in transmembrane domain 3 are major sites of α1b-adrenergic receptor antagonist binding. Biological and Pharmaceutical Bulletin. 30(10): 1891-4 (2007)

19. Muntasir HA, Hossain M, Bhuiyan MA, Komiyama T, Nakamura T, Ozaki M, Nagatomo T. Identification of a key amino acid of the human 5-HT2B serotonin receptor important for sarpogrelate binding. Journal of Pharmacological Sciences. 104(3): 274-7 (2007)

20. Miyajima K, Nakazawa M, Muntasir HA, Hossain M, Ahmed M and Nagatomo T. Differential inhibition by oxygen radicals of vasoactive amines-induced contraction in porcine coronary artery. Biological and Pharmaceutical Bulletin. 30(7):1242-1245 (2007)

21. Ahmed M, Muntasir HA, Hossain M, Ishiguro M, Komiyama T, Muramatsu I, Kurose H, Nagatomo T. Beta-blockers show inverse agonism to a novel constitutively active mutant of β1-adrenoceptor. Journal of Pharmacological Sciences. 102(2):167-72 (2006)

22. Muntasir HA, Takahashi J, Rashid M, Ahmed M, Komiyama T, Hossain M, Kawakami J, Nashimoto M, Nagatomo T. Site-directed mutagenesis of the serotonin 5-HT2C receptor: identification of amino acids responsible for sarpogrelate binding. Biological and Pharmaceutical Bulletin 29(8):1645-50 (2006)

23. Ahmed M, Muntasir HA, Ishiguro M, Komiyama T, Muramatsu I, Hossain M, Takahashi N and Nagatomo T. Pharmacological and Molecular Characterization of Novel SWR-Compounds for β1-adrenergic Receptors as Assessed by Molecular Modeling, Site-directed Mutagenesis, Binding Affinity and Functional Activity. Pharmacomatrics, 71 (1/2) 1-20 (2006)

24. Hossain M, Ali MS, Saha A, Alimuzzaman M. Antinociceptive activity of whole plant extracts of Paederiafoetida, Dhaka University Journal of Pharmaceutical Science, 5, 67-69 (2006)

COMMUNICATION & PRESENTATION

1. Hossain M, Safratwich BD, Carvelli L, Multiple exposures to AMPH induced desensitization of the dopaminergic system in living animals. Poster presentation in the Society for Neuroscience 41st Annual Meeting in Washington DC Convention Center on November from 12 to 16th, 2011, abstract published (444.08/D22).

2. Hossain M, Bhuiyan MA and Nagatomo T. Mutagenesis of important amino acid reveals unconventinal homologous internalization of β1-adrenergic receptor. Oral presentation in the 83rd Annual Meeting of the Japanese Pharmacological Society in Osaka Grand Cube Convention Center on March 16-18, 2010, abstract published (AS2C-2-3).

3. Hossain M, Bhuiyan MA and Nagatomo T. Assessment of binding affinity to 5-HT2A receptor and inverse agonist activity of naftidrofuryl: comparison with those of sarpogrelate. Poster presentation in the 11th OyoYakuri/Pharmacometrics conference on September 26, 2009 in Niigata University of Pharmacy and Applied Life Sciences.

4. Bhuiyan MA, Hossain M, and Nagatomo T. Angiotensin II receptor antagonists induce homologous internalization in constitutively active mutant N111G of AT1 receptor” Oral presentation in the 60thConference of Japanese Pharmacological Societyon September 27, 2009, in Toyama, Japan, abstract published (B-II-1).

5. Hossain M, Bhuiyan MA, Aly SAR, Shoe S and Nagatomo T. Evaluation of binding and functional potency of naftidrofuryl to human recombinant 5-HT2A receptor: comparison with sarpogrelate. Oral presentation in the 14th Serotonin Conference on February 7, 2009, in Tokyo, Japan, abstract published (I-1).

6. Bhuiyan MA, Hossain M, Aly SAR, Ishiguro M, Miura S-I and Nagatomo T. Assessment of valsartan for binding affinity and functional potency towards angiotensin ii type 1 (AT1) receptors. Oral presentation in the 59th Conference of Japanese Pharmacological Society on September 27, 2008, in Sendai, Japan, abstract published (C-II-5).

7. Muntasir HA, Bhuiyan MA, Hossain M, and Nagatomo T. Evaluation of Mechanism of Inverse Agonist Action of Sarpogrelate by Molecular Modeling. Oral presentation in the 13th Serotonin Conference on February 2, 2008, in Tokyo, Japan, abstract published (I-1).

8. Hossain M, Bhuiyan MA and Nagatomo T. Inverse agonism of β-blockers to a novel constitutive active mutant of β1-adrenergic receptor. Oral presentation in 5th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects.Grandship (Shizuoka Convention and Art Center), Shijuoka, Japan, May 10th –May 11th, 2007 Abstract published (P22)

9. Hossain M, Ahmed M, Ishiguro M and Nagatomo T. Beta adrenergic antagonists show inverse agonism to a novel constitutively active mutant of β1-adremergic receptor. Oral presentation in the 50th Japan Pharmaceutical Seminar.October 14-15, 2006, Niigata, Japan, abstract published (H05)

10. Muntasir HA, Bhuiyan MA, Hossain M, Kawakami J, Ishiguro M, Komiyama T and Nagatomo T. Inverse Agonist Activity of several 5-HT2A Receptor Antagonists at the Constitutively Active Human 5-HT2A Receptor. Oral presentation in the 34th Symposium on Structure Activity Relationship. November 14-15, 2006, Niigata, Japan, full paper and abstract published (KP07).

1.      Ulla A, Mohamed MK, Sikder B, Rahman AT, Sumi FA, Hossain M, Reza HM, Rahman GMS, Alam MA. Coenzyme Q10 prevents oxidative stress and fibrosis in isoprenaline induced cardiac remodeling in aged rats. BMC Pharmacol Toxicol, 18(1):29 (2017)

Rotary Yoneyama Memorial Foundation Scholarship for PhD study at Niigata, Japan.

Doctor of Philosophy (Ph.D.) in Pharmacy                                                                   April, 2007-March, 2010

Niigata University of Pharmacy and Applied Life Sciences, Japan.

Master of Science (M. Pharm.) in Pharmacy                                                                April, 2005-March, 2007

Niigata University of Pharmacy and Applied Life Sciences, Japan.

Bachelor of Science (B. Pharm.) in Pharmacy                                                            June, 1997-July, 2001

Faculty of Pharmacy, University of Dhaka, Bangladesh.

(Exam was held in 2004, due to session jam)

Assistant Professor  (September, 2014- Present)

Department of Pharmaceutical Sciences, University of North South, Bangladesh

Assistant Professor  (February, 2014- September, 2014)

Department of Pharmacy, University of Asia Pacific, Bangladesh

Postdoctoral Research Associate  (November, 2013-December, 2013)

University of Illinois at Chicago, USA

Postdoctoral Research Fellow  (November, 2010-October 2013)

University of North Dakota, USA

Postdoctoral Research Fellow  (April, 2010-October, 2010)

Niigata University of Pharmacy and Applied Life Sciences, Japan.

Courses for Spring 2016:
1. PHR 114: Organic Pharmacy-I
2. PHR 215: Medicinal Chemistry-I
3. PHR 5201: Drug Design
  • Member of the society for Neuroscience, USA.
  • Member of the Japanese Pharmacological Society (JPS), Japan.
  • Member of Bangladesh Society of Toxicology (BDSOT), Bangladesh
  • Member of Bangladesh Pharmaceutical Society (BPS), Bangladesh.
1. Neuropharmacology
2. Hepatotoxicity
3. Cardiovascular disease
Full Time Faculty
Assistant Professor

MPharm. & Ph.D., Niigata University of Pharmacy and Applied Life Sciences, Japan
BPharm., Faculty of Pharmacy, University of Dhaka, Bangladesh.

Phone: +880-2-55668200 Ext: 1961
Email: murad.hossain@northsouth.edu
Office: SAC1067

Curriculum Vitae