PHR 314 - Biopharmaceutics & Pharmacokinetics-I |
| Course Detail: |
This course includes the techniques used to assess the availability of the pharmaceutical product inside the body so as to ensure its proper therapeutic efficacy. Importance; Gastro-intestinal absorption of drugs; Biological, physicochemical and dosage form considerations; Disintegration and dissolution of drugs; Distribution of drugs with important pharmacokinetic parameters; Interpretation of drug-plasma level curve; Drug-protein interaction; Theoretical aspects of drug clearance; Elimination, excretion and biotransformation; Renal pathway of elimination; Hepatic elimination; Biliary excretion; Purpose of bioavailability; Methods of assaying bioavailability; Criteria for bioequivalence studies; Drug product selection on the basis of bioavailability testing.
[Pre-requisite: ]
[Credit Hours: 3] |
| Recommended Books: |
1. Biopharmaceutics & Clinical Pharmacokinetics. M. Gibaldi.
2. Biopharmaceutics & Clinical Pharmacokinetics. Notari.
3. Pharmacokinetics. M. Gibaldi & D. Perrier. |
