MIC 309 - Enzymology |
| Course Detail: |
The properties and functions of enzymes, cofactors, coenzymes and vitamins; Nomenclature and classification of enzyme, general classification, isoenzymes and multi-enzymes, allosteric enzymes; Structure of enzymes- primary, secondary, tertiary and quarternary structure, folding and domains, molecular chaperones; Kinetics of enzyme catalyzed reaction- factors influencing catalytic activity, simple enzyme kinetics with simple and multi substrate, Michaelis Menten kinetics: turnover number, Km and Vmax, other influences on enzyme activity, PH, temperature, fluid forces, chemical agents and irradiation; Enzyme inhibition and deactivation- competitive, non competitive and un competitive inhibition, deactivation model and strategies for enzyme stabilization.
[Pre-requisite: ]
[Credit Hours: 3] |
