Center of Excellence in Higher Education
The First Private University in Bangladesh

Dr. Ferdous Khan

Full Time Faculty
Assistant Professor

Ph.D, Tottori University, Japan

Phone: +880-2-55668200 Ext:
Email: khan.ferdous@northsouth.edu
Office: SAC 1014

Curriculum Vitae

 

Dr. Ferdous Khan received PhD degree from The United Graduate School of Agricultural Sciences, Tottori University, Japan under the supervision of Professor Dr. Kazushige Yokota. His doctoral study mainly focused on the molecular pharmacology and pathogenesis of obesity. His study involved extensive works on different cell lines as well as animal models like mice. His research theme was “Specific action of prostacyclin on adipogenesis at different stages of cultured adipocytes”. He revealed important roles of several transcription factors and bioactive lipids in the differentiaition and maturation of 3T3-L1 preadipocytes which would help in the drug discovery and development of diabetes resistance, obesity, hypertension and related metabolic disorders. Before going to Japan Dr. Ferdous Khan completed BPharm and MPharm degrees from the University of Dhaka. During his MPharm he secured First Class First position in the Department of Pharmaceutical Technology with highest score in the Faculty of Pharmacy.

Now he is working as an Assistant Professor in the Department of Pharmaceutical Sciences, North South University, Bangladesh. He also worked as a Lecturer and Assistant Professor in Department of Pharmacy of State University of Bangladesh, ASA University Bangladesh and Daffodil International University. Beside academia he also worked at Beximco Pharmaceuticals Ltd as a Quality Control Officer.
  1. Selim S, Akter N, Nayan SI, Chowdhury FI, Saffoon N, Khan F, Ahmed KS, Ahmed MI, Hossain MM, Alam MA. Flacourtia indica fruit extract modulated antioxidant gene expression, prevented oxidative stress and ameliorated kidney dysfunction in isoprenaline administered rats. Biochem Biophys Rep. 2021 May 18;26:101012. doi: 10.1016/j.bbrep.2021.101012. PMID: 34041370; PMCID: PMC8142055.
  2. Alam, M.A., Islam, P., Subhan, N. Rahman, M.M., Khan, F., Burrows, G.E., Nahar, L., Sarker, S.D. Potential health benefits of anthocyanins in oxidative stress related disorders. Phytochem Rev 20, 705–749 (2021). https://doi.org/10.1007/s11101-021-09757-1
  3. Miah P, Mohona SBS, Rahman MM, Subhan N, Khan F, Hossain H, Sharker SM, Alam MA. Supplementation of cumin seed powder prevents oxidative stress, hyperlipidemia and non-alcoholic fatty liver in high fat diet fed rats. Biomed Pharmacother. 2021 Jul 10;141:111908. doi: 10.1016/j.biopha.2021.111908. Epub ahead of print. PMID: 34328087.
  4. Shariful Islam Nayan1, Faizul Islam Chowdhury1, Noushin Akter, Md. Mizanur Rahman1,2, Saima Selim, Nadia Saffoon, Ferdous Khan, Nusrat Subhan, Maqsud Hossain, K. Shahin Ahmed, Hemayet Hossain, Md Areeful Haque Md Ashraful Alam (2021) Leaf powder supplementation of Senna alexandrina ameliorates oxidative stress, inflammation, and hepatic steatosis in high-fat diet-fed obese rats. PLoS ONE 16(4): e0250261. https://doi.org/10.1371/journal.pone.0250261
  5. Akter N, Chowdhury FI, Selim S, Nayan SI, Khan F, Subhan F, Hossain H, Rahman MM, Haque MA, Alam MA. Polyphenolics in ramontchi protect cardiac tissues via suppressing isoprenaline-induced oxidative stress and inflammatory responses in Long-Evans rats. Journal of Functional Foods. 75, (2020), 104250. https://doi.org/10.1016/j.jff.2020.104250.
  6. Kuddus SA, Bhuiyan MI, Subhan N, Shohag MH, Rahman A, Hossain MM, Alam MA and Khan F. Antioxidant-rich Tamarindus indica leaf extract reduced high-fat diet-induced obesity in rat through modulation of gene expression. Clinical Phytoscience 6, 68 (2020). https://doi.org/10.1186/s40816-020-00213-9.
  7. Raquibul Hasan, Shoumen Lasker, Ahasanul Hasan, Farzana Zerin, Mushfera Zamila, Faisal Parvez, Md. Mizanur Rahman, Ferdous Khan, Nusrat Subhan & Md. Ashraful Alam. Canagliflozin ameliorates renal oxidative stress and inflammation by stimulating AMPK–Akt–eNOS pathway in the isoprenaline-induced oxidative stress model. Sci Rep 10, 14659 (2020). https://doi.org/10.1038/s41598-020-71599-2.
  8. Raquibul Hasan, Shoumen Lasker, Ahasanul Hasan, Farzana Zerin, Mushfera Zamila, Faizul Islam Chowdhury, Shariful Islam Nayan, Md. Mizanur Rahman, Ferdous Khan, Nusrat Subhan & Md. Ashraful Alam. Canagliflozin attenuates isoprenaline-induced cardiac oxidative stress by stimulating multiple antioxidant and anti-inflammatory signaling pathways. Sci Rep 10, 14459 (2020). https://doi.org/10.1038/s41598-020-71449-1.
  9. Syed A. Kuddus, Zarin Tasnim, Md. Hasanuzzaman Shohag, Tahmina Yasmin, Md. Sahab Uddin, Muhammad M. Hossain, Nusrat Subhan, Md. Ashraful Alam and Ferdous Khan. “Dillenia indica fruit extract suppressed diet-induced obesity in rat by down-regulating the mRNA level of proadipogenic transcription factors and lipid metabolizing enzymes”, Curr Nutr & Food Sc (2020) 16: 1. https://doi.org/10.2174/157340131699920090
  10. Fariha Mamun, Shoumen Lasker, Ferdous Khan, Tahmina Yasmin, Khondker Ayesha Akter, Nusrat Subhan, Md Ashraful Alam. Etoricoxib treatment prevented body weight gain and ameliorated oxidative stress in the liver of high-fat diet-fed rats. 2020. Naunyn Schmiedebergs Arch Pharmacol. 2020;10.1007/s00210-020-01960-9. doi:10.1007/s00210-020-01960-9.
  11. Ferdous Khan, Syed Abdul Kuddus, Md. Hasanuzzaman Shohag, Hasan Mahmud Reza, Murad Hossain. Astaxanthin, the natural antioxidant, reduces reserpine induced depression in mice. Current Bioactive Compounds. (2020) 16: 1319. https://doi.org/10.2174/1573407216666200203142722
  12. Golam K, Palash K, Shahid MS, Abhijit D, Hasanuzzaman M, Khan F, Rafiquzzaman M, Islam MS. 2017. Comparative study of antidiabetic effect of some selected plants extract from Cucurbitaceae family in alloxan-induced diabetic mice. Journal of Noakhali Science and Technology University (JNSTU), 1(2):9-18.
  13. Khan F, Syeda PK, Nartey MN, Rahman MS, Islam MS, Nishimura K, Jisaka M, Shono F, Yokota K. 2016. Pretreatment of cultured preadipocytes with arachidonic acid during the differentiation phase without a cAMP-elevating agent enhances fat storage after the maturation phase. Prostaglandins Other Lipid Mediat. 123(27):16-27.
  14. Khan F, Syeda PK, Nartey MN, Rahman MS, Islam MS, Nishimura K, Jisaka M, Shono F, Yokota K. 2016. Stimulation of fat storage by prostacyclin and selective agonists of prostanoid IP receptor during the maturation phase of cultured adipocytes. Cytotechnology 68(6):2417-2429.
  15. Rahman MS, Khan F, Syeda PK, Nishimura K, Jisaka M, Nagaya T, Shono F, Yokota 2014. Endogenous synthesis of prostacyclin was positively regulated during the maturation phase of cultured adipocytes. Cytotechnology 66(4):635-46.
  16. Rahman MS, Syeda PK, Khan F, Nishimura K, Jisaka M, Nagaya T, Shono F, Yokota K. 2013. Cultured preadipocytes undergoing stable transfection with cyclooxygenase-1 in the antisense direction accelerate adipogenesis during the maturation phase of adipocytes. Appl Biochem Biotechnol. 171(1):128-44.
  17. Syeda PK, Hossain MS, Chowdhury AA, Rahman MS, Khan F, Nishimura K, Jisaka M, Nagaya T, Shono F, Yokota K. 2012. A monoclonal antibody specific for Δ12-prostaglandin J2 and its utilization in the immunological assay in cell culture system of adipocytes. Hybridoma (Larchmt). 31(5):364-71.
  18. Shaikhul Millat Ibn Razzak, Ferdous Khan, Masuma Hossain, Tasmia Anika and Shamsad Afreen Moon, 2012. Impact of Sodium Lauryl Sulphate on the Release of Carbamazepine from Methocel K15M CR based Matrix Tablets. Bangladesh Pharmaceutical Journal. 15(1): 79-82.
  19. Khan, F., Razzak, M.S.M.I., Khan, M.Z.R., Azad, M.A.K., Chowdhury, J.A. and Reza, M.S. 2009. Theophylline Loaded Gastroretentive Floating Tablets Based on Hydrophilic Polymers: Preparation and in vitro Pakistan Journal of Pharmaceutical Sciences. 22 (2): 155-161.
  20. Razzak, M.S.M.I., Khan, F., Hossain, M., Khan, M.Z.R., Azad, M.A.K., and Reza, M.S. 2009. Effect of Channeling Agents on the Release Pattern of Theophylline from Kollidon SR Based Matrix Tablets. Pakistan Journal of Pharmaceutical Sciences. 22(3): 303-307.
  21. Khan, F., Razzak, M.S.M.I., Khan, M.Z.R., Azam, K.R., Sadat, S.M.A. and Reza, M.S. 2008. “Preparation and In vitro Evaluation of Theophylline Loaded Gastroretentive Floating Tablets of METHOCEL K4M”, The Dhaka University Journal of Pharmaceutical Sciences. 7(1): 65-70.
  22. Razzak, M.S.M.I., Khan, F., Khan, M.Z.R., Fatema, K., Islam, M.S. and Reza, M.S. 2008. “Effect of Channeling Agents on the Release Profile of Theophylline from METHOCEL K4M Based Matrix tablets” The Dhaka University Journal of Pharmaceutical Sciences 7(1): 27-32.
  23. Azam, K.R., Razzak, M.S.M.I., Khan, F., Islam, M.S., Rony, M.R. and Reza, M.S. 2008. Impact of Granulation Technique and Effect of Polymers on Theophylline Release from Matrix Tablets. The Dhaka University Journal of Pharmaceutical Sciences. 7(2): 133-139.
  24. Ferdous Khan, Younus Patoare, Pinky Karim, Mohiuddin Abdul Quadir, Israt Rayhan, and Abul Hasnat, 2005. Effect of magnesium and zinc on the antimicrobial activities of some antibiotics against different strains of microorganism. Pakistan Journal of Pharmaceutical Sci 18(4): 57-61.
  1. Received Japanese Government Monbukagakusho Scholarship (MEXT) from October 2011 to September 2014 for pursuing PhD as a graduate student of The United Graduate School of Agricultural Sciences, Tottori University, Japan.
  2. Became Summa cum laude in the Master of Pharmaceutical Technology examination of year 2002 (held in 2006) form Department of Pharmaceutical Technology, University of Dhaka, Bangladesh.
  3. Received Elementary school level, Junior high school level and Secondary scholarships. 

Ph.D.

  • Awarded on 16th September 2016
  • From The United Graduate School of Agricultural Sciences, Tottori University, Japan
  • Subject of the Thesis: Specific action of prostacyclin on adipogenesis at different stages of cultured adipocytes
  • Major Contribution: Proposed a new mechanism of adipogenesis which can be considered for drug development

 M. Pharm.:

  • Completed M. Pharm. from the Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka in the year of 2002 (held in 2006) with first class first position.
  • Marks obtained: 73.67 %.

B. Pharm.:

  • Completed B. Pharm. From the Faculty of Pharmacy, University of Dhaka in the year of 2001(held in 2004) with first class eleventh position.
  • Marks obtained: 65.43%.

Higher Secondary School Certificate (HSC) Examination:

  • Passed from Dhaka College, Dhaka under Dhaka Board in the year of 1997 (Science Group) with first division.

Secondary School Certificate (SSC) Examination:

  • Passed from Goila High School, Barisal under Jessore Board in the year of 1994 (Science Group) with first division.
  1. Currently, he is working as an Assistant Professor in Department of Pharmaceutical Sciences under the School of Health and Life Sciences, North South University, Bangladesh.
  1. He worked as an Assistant Professor in Department of Pharmacy, Daffodil International University from 2 May 2015 to 19 July 2016. He performed the responsibility of Head (In-Charge) from 29 September 2015 to 19 July 2016 before joining to NSU.
  2. He served as an Assistant Professor in Department of Pharmacy, ASA University Bangladesh, on 1st February 2011 and worked until 30th September 2011 before going to Japan as a graduate student of Doctoral Program of The United Graduate School of Agricultural Sciences, Tottori University.
  3. He was appointed as a Lecturer in the Department of Pharmacy, State University of Bangladesh on 2nd July 2005 and was promoted to Assistant Professor on 1st March 2010. I worked as an Assistant Professor in the Department of Pharmacy, State University of Bangladesh until 31st January 2011.
  • He worked as a Quality Control Officer in Beximco Pharmaceuticals Ltd., the 2nd largest pharmaceutical company of Bangladesh from 19th August 2004 to 1st July 2005.
  • Clinical Toxicology and Safety Pharmacology
  • Advanced Pharmacology I and II
  • Pathology and Toxicology
  • Pharmaceutical Microbiology
  • Human Physiology
  • Biopharmaceutics and Pharmacokinetics
  • Molecular Biology and Biochemistry
  • Editorial Board member of International Journal of Applied Research
  • BPS (2007-) Bangladesh Pharmaceutical Society Association.
  • PGA (2007-) Pharmacy Graduates Association, Bangladesh.

Now, Dr. Khan is interested to explore the genetic background of adipogenesis. More specifically, how different type of bioactive lipids and food ingredients can alter the expression of pro-adipogenic and anti-adipogenic genes. In this way he would like to shed some light on the on-going stride to understand obesity and related disorders which ultimately causes metabolic syndrome: the greatest threat to humankind.