Center of Excellence in Higher Education
The First Private University in Bangladesh

Dr. Asim Kumar Bepari

Full Time Faculty
Professor 

PhD (Neuroscience), Kumamoto University, Japan
MPharm, Jahangirnagar University, Bangladesh

Email: asim.bepari@northsouth.edu
Curriculum Vitae

 Scopus Author ID: 54398230600                      ResearcherID: D-4001-2013
 ORCID icon http://orcid.org/0000-0001-5656-1833
 
 
 

Dr. Asim Kumar Bepari is passionate for teaching and research. His works are aiming in understanding pathophysiology of human diseases, and in the long run, finding better therapeutic interventions to improve quality of life. He obtained his Bachelor of Pharmacy Honors (BPharm Honors) and Master of Pharmacy (MPharm) from Jahangirnagar University, Bangladesh. He is a registered pharmacist (A-Grade) with the Pharmacy Council of Bangladesh. During undergraduate and graduate studies in pharmaceutical sciences Dr. Bepari worked on market status and quality of antibacterial agents. In 2002, Dr. Bepari started his career in The Acme Laboratories Ltd. which is a leading pharmaceutical company in Bangladesh. In Acme, he developed strong leadership, communication and administrative skills while working as an executive and later as the coordinator of the International Marketing section.

Dr. Bepari started his journey as a teacher in the Department of Pharmacy at Stamford University Bangladesh (SUB) from 2004 and then switched to the North South University (NSU), Bangladesh in 2007. Since NSU Pharmacy was at a nascent stage at that time, Dr. Bepari had the opportunity to experience and to be actively involved in the rapid progress of the department. He was in Kumamoto University, Kumamoto, Japan for his doctoral study (2009-2013) in life sciences. For mapping brain activity he utilized different sophisticated techniques of molecular and cellular neuroscience using in vivo (mouse, chick) and cell culture models. His research findings were published in high impact peer reviewed international journals. Dr. Bepari worked as a guest researcher (Jan-Dec, 2012) and as a postdoctoral researcher (Apr-Jun, 2013) in the laboratory of Professor Dr. Hirohide Takebayashi in the Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

At NSU Pharmacy, Dr. Bepari has been teaching several courses including human phyiology, pharmaceutical analysis and pharmaceutical chemistry. He is also an external examiner of Jahangirnagar University from 2005. In collaboration with Professor Hirohide Takabayashi’s research group in Japna and with fellow researchers at NSU, Dr. Bepari is working on several projects including brain lateralization and molecular mechanisms regulating nervous system development. Dr. Bepari completed his posdoctoral training in the University of Texas Southwestern Medical Centre, Dallas, Texas, USA.

   

1.                

Bepari AK, Shatabda S, Reza HM. Virtual screening of flavonoids as potential RIPK1 inhibitors for neurodegeneration therapy. PeerJ. 2024;12.

2.                

Bepari AK, Rabbi G, Shaon HR, Khan SI, Zahid ZI, Dalal K, Reza HM. 2023a. Factors Driving Antimicrobial Resistance in Rural Bangladesh: A Cross-Sectional Study on Antibiotic Use-Related Knowledge, Attitude, and Practice Among Unqualified Village Medical Practitioners and Pharmacy Shopkeepers. Advances in Therapy 40:3478–3494. DOI: 10.1007/s12325-023-02547-5.

3.                

Johra, F.T., Hossain, S., Jain, P., Bristy, A.T., Emran, T., Ahmed, R., Sharker, S.M., Bepari, A.K. and Reza, H.M., 2023. Amelioration of CCl4-induced oxidative stress and hepatotoxicity by Ganoderma lucidum in long evans rats. Scientific Reports, 13(1), p.9909.

4.                

Bepari, A.K., Rabbi, G., Shaon, H.R., Khan, S.I., Zahid, Z.I., Dalal, K. and Reza, H.M., 2023. Factors Driving Antimicrobial Resistance in Rural Bangladesh: A Cross-Sectional Study on Antibiotic Use-Related Knowledge, Attitude, and Practice Among Unqualified Village Medical Practitioners and Pharmacy Shopkeepers. Advances in Therapy, pp.1-17.

5.                

Namme, J.N., Reza, H.M. and Bepari, A.K., 2023. Computational analysis and molecular dynamics simulation of high-risk single nucleotide polymorphisms of the ADAM10 gene. Journal of Biomolecular Structure and Dynamics, pp.1-13.

6.                

Hossain M, Suchi TT, Samiha F, Islam MM, Tully FA, Hasan J, Rahman MA, Shill MC, Bepari AK, Rahman GS, Reza HM. Coenzyme Q10 ameliorates carbofuran induced hepatotoxicity and nephrotoxicity in wister rats. Heliyon. 2023 Feb 14.

7.                

Bepari AK, Takebayashi H, Namme JN, Rahman GM, Reza HM. A computational study to target necroptosis via RIPK1 inhibition. Journal of Biomolecular Structure and Dynamics. 2022 Jul 30:1-6.

8.                

Rahman MA, Shuvo AA, Bepari AK, Hasan Apu M, Shill MC, Hossain M, Uddin M, Islam MR, Bakshi MK, Hasan J, Rahman A. Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies. Plos one. 2022 Jun 29;17(6):e0270123.

9.                

Shill MC, Biswas B, Islam M, Rima SS, Ferdausi FA, Chowdhury Q, Reza HM, Bepari AK. 2022. Screening of plasma IL-6 and IL-17 in Bangladeshi lung cancer patients. :2022.03.27.22272998. DOI: 10.1101/2022.03.27.22272998.

10.             

Jain P, Bepari AK, Sen PK, Rafe T, Imtiaz R, Hossain M, Reza HM. High prevalence of multiple antibiotic resistance in clinical E. coli isolates from Bangladesh and prediction of molecular resistance determinants using WGS of an XDR isolate. Scientific reports. 2021 Nov 24;11(1):22859.

11.             

Bizen N, Bepari AK, Zhou L, Sakimura K, Ono K, Takebayashi H. Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression. Cell Death Differ. Published online January 1, 2022:1-14. doi:10.1038/s41418-021-00915-8

12.             

Namme JN, Bepari AK*, Takebayashi H.* Cofilin Signaling in the CNS Physiology and Neurodegeneration. International Journal of Molecular Sciences. 2021 Jan;22(19):10727.

13.             

Shill MC, Bepari AK, Khan M, Tasneem Z, Ahmed T, Hasan MA, et al. Therapeutic Potentials of Colocasia affinis Leaf Extract for the Alleviation of Streptozotocin-Induced Diabetes and Diabetic Complications: In vivo and in silico-Based Studies. Journal of Inflammation Research. 2021 Feb 19;14:443–59.

14.             

Emran T, Chowdhury NI, Sarker M, Bepari AK, Hossain M, Rahman GMS, et al. L-carnitine protects cardiac damage by reducing oxidative stress and inflammatory response via inhibition of tumor necrosis factor-alpha and interleukin-1beta against isoproterenol-induced myocardial infarction. Biomedicine & Pharmacotherapy. 2021 Nov 1;143:112139.

15.             

Bepari AK, Reza HM. Identification of a novel inhibitor of SARS-CoV-2 3CL-PRO through virtual screening and molecular dynamics simulation. PeerJ. 2021 Apr 13;9:e11261.

16.             

Bari R, Bepari AK, Reza HM. COVID-19: Lessons from Norway tragedy must be considered in vaccine rollout planning in least developed/developing countries. Open Medicine. 2021;16(1):1168–9.

17.             

Akash SZ, Lucky FY, Hossain M, Bepari AK, Rahman GM, Reza HM, et al. Remote Temperature-Responsive Parafilm Dermal Patch for On-Demand Topical Drug Delivery. Micromachines. 2021;12(8):975.

18.             

Reza HM, Saleh R, Jain P, Rahman GMS, Bepari AK. C-MAF Expression in Adult Human Ocular Surface and its Implication in Pterygium Pathogenesis. Reports of Biochemistry and Molecular Biology. 2020 Jan 10;8(4):419–28.

19.             

Johra FT, Bepari AK, Bristy AT, Reza HM. A Mechanistic Review of β-Carotene, Lutein, and Zeaxanthin in Eye Health and Disease. Antioxidants. 2020 Nov;9(11):1046.

20.             

Toda, H., Kawasaki, K., Sato, S., Horie, M., Nakahara, K., Bepari, A.K., Sawahata, H., Suzuki, T., Okado, H., Takebayashi, H., Hasegawa, I., 2018. Locally induced neuronal synchrony precisely propagates to specific cortical areas without rhythm distortion. Scientific Reports. 2018;8(1). doi:10.1038/s41598-018-26054-8.

21.             

Pohlkamp T, Xiao L, Sultana R, Bepari A, Bock HH, Henkemeyer M, et al. Ephrin Bs and canonical Reelin signalling. Nature. 2016 Nov;539(7630):E4–6.

22.             

Horie M, Watanabe K, Bepari AK, Nashimoto J, Araki K, Sano H, et al. Disruption of actin-binding domain-containing Dystonin protein causes dystonia musculorum in mice. European Journal of Neuroscience. 2014 Nov;40(10):3458–71.

23.             

Bepari AK, Watanabe K, Yamaguchi M, Tamamaki N, Takebayashi H. Visualization of odor-induced neuronal activity by immediate early gene expression. BMC Neuroscience. 2012 Nov 5;13(1):140.

24.             

Bepari AK, Sano H, Tamamaki N, Nambu A, Tanaka KF, Takebayashi H. Identification of Optogenetically Activated Striatal Medium Spiny Neurons by Npas4 Expression. PLoS ONE. 2012 Dec 26;7(12):e52783.

25.             

Watanabe K, Takebayashi H, Bepari AK, Esumi S, Yanagawa Y, Tamamaki N. Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex. Development. 2011 Nov 15;138(22):4979–90.

2011

Financial support for young scientists, Global COE, Kumamoto University, Japan.

2011

GCOE Travel Award for Young Scientists, Global COE, Kumamoto University, Japan.

2011

Global COE Jr. Research Associate, Global COE, Kumamoto University, Japan

2009 to 2013

Monbukagakusho Fellowship for doctoral study, MEXT, Japan.

1996 to 2001

Jahangirnagar University Undergraduate and Postgraduate Scholarship for excellent academic results in B.Pharm (Honours) and M.Pharm.

2013

PhD in Life Sciences

Faculty of life Sciences, Kumamoto University, Japan

Supervisors: Professor Nobuaki Tamamaki, Professor Hirohide Takebayashi

Thesis title: Mapping neuronal activity in the mouse brain by analyzing immediate early gene expression.

 

 

2002

 

Master of Pharmacy (Research)

Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh

Thesis title: Market status of antibacterial agents and in vitro quality studies of amoxicillin trihydrate and its marketed capsule preparations.

 

 

2000

 

Bachelor of Pharmacy (Honors)

Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh

2023-Nov-01 to date

Professor

Department of Pharmaceutical Sciences
School of Health and Life Sciences, North South University, Dhaka, Bangladesh

2018 to 2023

Associate Professor

Department of Pharmaceutical Sciences
School of Health and Life Sciences, North South University, Dhaka, Bangladesh

2013 to 2018

Assistant Professor (on leave from April 2015 to May 2017)

Department of Pharmaceutical Sciences
School of Health and Life Sciences, North South University, Dhaka, Bangladesh

2015 to 2017

Postdoctoral Researcher

Department of Neuroscience
University of Texas Southwestern Medical Centre Dallas, Texas, USA

Supervisor: Prof. Dr. Mark Henkemeyer

2013

Postdoctoral Researcher

Division of Neurobiology and Anatomy
Graduate School of Medical and Dental Sciences, Niigata University, Japan.

2009 to 2013

Doctoral Researcher

Department of Morphological Neural Science
Faculty of life sciences, Kumamoto University, Japan.

2007 to 2013

Junior Lecturer (on study leave from 2009 to 2013)

Department of Pharmacy, North South University, Dhaka.

2004 to 2006

Lecturer

Department of Pharmacy, Stamford University Bangladesh, Dhaka, Bangladesh

2002 to 2004

Executive

Division of International Marketing
The ACME Laboratories Limited, Dhaka, Bangladesh

  • Coordinated international marketing operations of pharmaceutical finished products for countries like Australia, China, India, Sri Lanka, and Pakistan.
  • Major duties involved identification and development of international markets for medical products, drafting business agreements, preparation of marketing plans, development of promotional materials, preparation of reports, participation in international meetings and exhibitions.
  • Advanced Pharmacology I
  • Pharmacotherapy
  • Advanced Pharmaceutical Analysis
  • Pharmaceutical Analysis II
  • Biostatistics
  • Drug development for injury-induced hyperalgesis
  • Drug development for Alzheimer's disease
  • Brain development
  • Ephs and Ephrins
  • Activity-dependent genes